17620-38-1Relevant articles and documents
METABOLITES OF 2-{3-[4-(2-ISOPROPOXYPHENYL) PIPERAZIN-1-YL]-PROPYL}-3A,4,7,7A-TETRAHYDRO-1H-ISOINDOLE-1,3-(2H)-DIONE
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Page/Page column 54, (2010/11/23)
The present invention relates to the metabolites of 2-{3-[4-(2-isopropoxyphenyl) piperazin-1-yl]-propyl}-3a,4,7,7a -tetrahydro-1H-isoindole-1,3(2H)-dione of Formula I. The disclosed compounds can function as 1a-adrenoceptor antagonists and thus can be used for the treatment of benign prostatic hyperplasia (BPH) and related symptoms thereof. Processes for preparing the metabolites, pharmaceutical composition containing these metabolites and the method of treating BPH and related symptoms thereof are also provided.
ADRENERGIC RECEPTOR ANTAGONISTS
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Page/Page column 85, (2008/06/13)
The present invention relates to α1a and/or α1d adrenergic receptor antagonists, which can function as α1a and/or α1d adrenergic receptor antagonist and can be used for the treatment of a disease or disorder med