176383-19-0Relevant articles and documents
BENZODIAZEPINE PRODUCT WITH ACTIVITY ON THE CENTRAL NERVOUS AND VASCULAR SYSTEMS
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Paragraph 0098, (2019/09/16)
Formula III compound, its products and pharmaceutical compositions containing them for the treatment of central nervous and vascular system diseases, particularly neurodegenerative disorders with cognitive deterioration, diseases associated with oxidative
Steric and electronic substitution effects on the thermal oxidation of 5-carboethoxy-2-oxo-1,2,3,4-tetrahydropyridines
Memarian, Hamid Reza,Kalantari, Mahdieh
, p. 143 - 155 (2017/01/05)
Various 4-aryl substituted 5-carboethoxy-2-oxo-1,2,3,4-tetrahydropyridines were oxidized to their corresponding 4-aryl-5-carboethoxy-2-oxo-1,2-dihydropyridines by potassium peroxydisulfate in aqueous acetonitrile under thermal conditions. The products wer
High-throughput preparation of alkyl 4-aryl substituted-2-methyl-6-thioxo- 1,4,5,6-tetrahydropyridine-3-carboxylates under microwave irradiation
Rodriguez, Hortensia,Coro, Julieta,Lam, Anabel,Salfran, Esperanza,Rodriguez-Salarichs, Javier,Suarez, Margarita,Albericio, Fernando,Martin, Nazario
experimental part, p. 125 - 141 (2011/08/07)
An efficient high-throughput synthesis of 4-aryl substituted 1,4,5,6-tetrahydro-2-methyl-6-thioxopyridine-3-carboxylates 5a-p was developed by using Lawesson's reagent, a very effective thionating reagent for carbonyl compounds, under conventional conditi
Novel hexahydrofuro[3,4-b]-2(1H)-pyridones from 4-aryl substituted 5-alkoxycarbonyl-6-methyl-3,4-dihydropyridones
Morales, Alhmed,Ochoa, Estael,Suarez, Margarita,Verdecia, Yamila,Gonzalez, Leandro,Martin, Nazario,Quinteiro, Margarita,Seoane, Carlos,Soto, Jose L.
, p. 103 - 107 (2007/10/03)
The title compounds 6 have been prepared in a one-step procedure from the corresponding 4-aryl substituted 5-alkoxycarbonyl-6-methyl-3,4-dihydropyridones 4 in good yields. Quantum chemical calculations reveal a non-planar molecule with a distorted dihydropyridone ring and two favoured conformations. The 13C nmr data and theoretical calculations support a strong push-pull effect on the olefinic moiety.