631-61-8 Usage
Chemical Description
Different sources of media describe the Chemical Description of 631-61-8 differently. You can refer to the following data:
1. Ammonium acetate is a salt composed of ammonium and acetate ions.
2. Ammonium acetate is a salt that is commonly used as a reagent in organic synthesis.
3. Ammonium acetate and glycine are used in the reductive amination step to prepare the auxiliaries.
Chemical Properties
Ammonium acetate is a white, deliquescent crystalline solid with a slightly acetic odor. It is used as a reagent in analytical chemistry for determining lead and iron content，a chemical intermediate in manufacturing acetamide. It is also a diuretic in veterinary medicine, in other drugs, in textile dyeing, in meat preservative, in foam rubbers, in vinyl plastics, in stripping explosives, and in determining lead and iron content.
Physical properties
White crystalline solid; deliquescent; melts at 114°C; decomposes at elevated temperatures; density 1.17 g/cm3 at 20°C, density of a 10% solution 1.022 g/mL, and a 50% solution 1.092 g/mL; very soluble in cold water (1,480 g/L at 4°C); also soluble in cold alcohol and acetone (78.9 g/L in methanol at 15°C); solution loses ammonia on standing and becomes acidic.
Uses
Different sources of media describe the Uses of 631-61-8 differently. You can refer to the following data:
1. Ammonium acetate is a reagent used in chromatographic analysis of various compounds such as oligos, proteins, and peptides. It is also employed with acetic acid to provide a buffer solution. Generally it behaves as a catalyst in many reactions like Knoevenagel, Borch. It is also employed as a nutrient additive.
2. Ammonium acetate solution can be used to study molecular biology, biological buffers, reagents and DNA and RNA purification. Ammonium acetate solution has been used to study pharmacokinetic analysis of α and β epimers of glycyrrhetinic acid in rat plasma. Ammonium acetate solution has also been used in a study to develop a method for the simultaneous determination of aristolochic acids A and B in some Chinese herbals and traditional Chinese patent medicines.
3. Ammonium acetate is used in the manufacture of acetamide and as a diuretic and diaphoretic in medical applications. The wool industry also uses this salt as a dye mordant.
Buffer solution; determination of lead and iron; separating lead sulfate from other sulfates.
Preparation
Ammonium acetate is manufactured by neutralizing acetic acid with ammonium carbonate or by passing ammonia gas into glacial acetic acid. Acidic ammonium acetate, CH3CO2NH4.CH3CO2H[25007-86-7], is manufactured by dissolving the neutral salt in acetic acid.
General Description
A white crystalline solid. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. Ammonium acetate is used in chemical analysis, in pharmaceuticals, in preserving foods, and for other uses.
Air & Water Reactions
Water soluble.
Reactivity Profile
Ammonium acetate causes the decomposition of sodium hypochlorite within a few seconds [Mellor 2 Supp. 1:550 1956].
Health Hazard
Inhalation of dust irritates nose and mouth. Ingestion irritates mouth and stomach. Contact with dust causes irritation of eyes and mild irritation of skin.
Fire Hazard
Special Hazards of Combustion Products: Irritating vapors of ammonia acetic acid, and nitrogen oxides may form in fires.
Flammability and Explosibility
Nonflammable
Biochem/physiol Actions
Ammonium acetate can be used in proteinaceous baits and in beer waste to increase their attraction to Ceratitis capitate. It helps in the progression of acetone-butanol-ethanol (ABE) fermentation when it is used as the only nitrogen source.
Safety Profile
Poison by intravenous route. Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of NO, and NH3
Potential Exposure
Ammonium acetate is used as a chemical
reagent, to make drugs; foam rubber; vinyl plastics;
explosives, and to preserve foods. An environmental threat.
Shipping
UN3077 Environmentally hazardous substances,
solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous
material, Technical Name Required.
Purification Methods
Crystallise it twice from anhydrous acetic acid, and dry under vacuum for 24hours at 100o [Proll & Sutcliff Trans Faraday Soc 57 1078 1961].
Incompatibilities
Combustible solid. Incompatible with
oxidizers (chlorates, nitrates, peroxides, permanganates,
perchlorates, chlorine, bromine, fluorine, etc.); contact may
cause fires or explosions. Keep away from alkaline materials,
strong bases, strong acids, oxoacids, epoxides, sodium
hypochlorite, potassium chlorate, sodium nitrite.
Check Digit Verification of cas no
The CAS Registry Mumber 631-61-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,3 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 631-61:
(5*6)+(4*3)+(3*1)+(2*6)+(1*1)=58
58 % 10 = 8
So 631-61-8 is a valid CAS Registry Number.
InChI:InChI=1/C2H4O2.H3N/c1-2(3)4;/h1H3,(H,3,4);1H3
631-61-8Relevant articles and documents
Method for preparing 3-amino-4,4,4-trifluorocrotonate
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Paragraph 0012; 0021; 0023, (2017/01/31)
The invention discloses a method for preparing 3-amino-4,4,4-trifluorocrotonate with high raw material utilization rate. According to the invention, 4,4,4-trifluoroacetyl ethyl acetate and excessive ammonium acetate are subjected to an amination reaction to obtain a reaction solution, then the reaction solution is separated to an organic phase and an aqueous phase, ammoniacal liquor is added in the aqueous phase to obtain ammonium acetate, and finally ammonium acetate is cycled to continuous reaction.
PROCESS FOR PREPARING AMINO ACIDS USING THE AMIDOCARBONYLATION REACTION (1)
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Page/Page column 12-13, (2008/06/13)
The present invention relates to a sequence for the preparation of amino acids, for example alpha amino acids, in particular methionine, by making use of an amidocarbonylation reaction and reuse of the catalyst.
PROCESS FOR PRODUCING LACTIDE AND PROCESS FOR PRODUCING POLYLACTIC ACID STARTING WITH FERMENTED LACTIC ACID
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Page/Page column 9-10, (2010/01/31)
According to the present invention, a process for consistently producing lactide from ammonium lactate obtained by lactic fermentation, and a process for consistently producing polylactic acid from ammonium lactate obtained by lactic fermentation, are provided. A process for producing lactide, which comprises the steps of: (1) synthesizing lactate ester from ammonium lactate obtained by lactic fermentation; (2) polycondensing the lactate ester in the presence of a catalyst other than monobutyltin, whereby polylactic acid with a weight-average molecular weight of less than 15,000 (lactic acid prepolymer) is synthesized; and (3) depolymerizing the polylactic, whereby lactide is produced. A process for producing polylactic acid, which comprises the additional step of (4) ring-opening polymerizing said lactide, whereby polylactic acid is obtained. A process for producing lactate ester from ammonium lactate obtained by lactic fermentation.
F:Highly flammable;
