17823-69-7

Basic information

• Product Name: 3,3-Bis(methylthio)-2-cyanopropenamide
• Synonyms: 2-Cyano-3,3-bis(methylthio)acrylamide;3,3-Bis(methylthio)-2-cyanopropenamide
• CAS NO: 17823-69-7
• Molecular Formula: C₆H₈N₂OS₂
• Molecular Weight: 188.27052
• Mol File: 17823-69-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 101-102 °C
• Boiling Point: 349.7±42.0 °C(Predicted)
• Appearance: /
• Density: 1.317±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 11.74±0.50(Predicted)
• CAS DataBase Reference: 3,3-Bis(methylthio)-2-cyanopropenamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-Bis(methylthio)-2-cyanopropenamide(17823-69-7)
• EPA Substance Registry System: 3,3-Bis(methylthio)-2-cyanopropenamide(17823-69-7)

Safety Data

• Hazardous Substances Data: 17823-69-7(Hazardous Substances Data)

Usage

General Description

3,3-Bis(methylthio)-2-cyanopropenamide is a chemical compound with the molecular formula C7H10N2OS2. It is known for its strong antibacterial and antifungal properties, making it a useful ingredient in various antimicrobial products. 3,3-Bis(methylthio)-2-cyanopropenamide is often used in industrial and agricultural applications, as well as in the formulation of personal care products and cosmetics. Its ability to inhibit the growth of microorganisms and fungi makes it a valuable component in many different products, contributing to their effectiveness in preventing contamination and promoting overall hygiene and safety. However, it is important to handle this compound with care, as it can be harmful if ingested or comes into contact with the skin or eyes.

Upstream product

• 118373-67-4 3,3-Dimercapto-2-cyanacrylamid 
• 77-78-1 dimethyl sulfate 
• 75-15-0 carbon disulfide 
• 107-91-5 cyanoacetic acid amide 
• 24571-59-3 3,3-bis(ammoniothio)-2-cyanoacrylamide 
• 74-88-4 methyl iodide 

Downstream Products

• 68192-60-9 6-(p-bromophenyl)-3-cyano-4-methylthio-2(1H)-pyridone 
• 57663-06-6 4-(methylthio)-2-oxo-6-phenyl-1,2-dihydropyridine-3-carbonitrile 
• 114388-32-8 3-cyano-5-methyl-4-methylthio-6-phenyl-2(1H)-pyridone 
• 57663-08-8 6-(4-methoxyphenyl)-4-(methylthio)-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 111324-19-7 5-phenyl-1,3,4-thiadiazolo<3,2-c>quinazolinylium-2-<(aminocarbonyl)cyanomethanide> 
• 61254-25-9 2-amido-1-(N-aziridino)-2-cyano-1-(methylthio)ethylene 
• 1055964-47-0 (2Z)-2-cyano-3-[(3-hydroxy-4-methoxyphenyl)amino]-3-(methylthio)acrylamide 
• 111324-37-9 5-(4-methoxyphenyl)-1,3,4-thiadiazolo<3,2-c>quinazolinylium-2-<(aminocarbonyl)cyanomethanide> 
• 111324-22-2 5-(4-methylphenyl)-1,3,4-thiadiazolo<3,2-c>quinazolinylium-2-<(aminocarbonyl)cyanomethanide> 
• 114361-61-4 3-cyano-1,2-dihydro-4-methylthio-6-phenyl-2-oxo-5-pyridylacetic acid 
• 57663-05-5 6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 130224-41-8 5-amino-3-methylthio-1-(p-nitrophenyl)pyrazole-4-carboxamide 
• 28559-55-9 3-cyano-1,2,9,10-tetrahydro-4-methylthio-2-oxobenzoquinoline 
• 130224-40-7 5-amino-4-carboxamido-1-(4-chlorophenyl)-3-(methylthio)pyrazole 

Relevant articles and documents

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3,5-DIAMINOPYRAZOLE KINASE INHIBITORS

Provided herein are 3,5-diaminopyrazoles, for example, compounds of Formula I, that are useful for modulating regulated-in-COPD kinase activity, and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventin

Synthesis and antiviral bioactivities of 2-cyano-3-substitutedamino(phenyl) methylphosphonylacrylates (Acrylamides) containing alkoxyethyl moieties

An efficient reaction under microwave irradiation has been developed for the synthesis of a series of novel 2-cyano-3-substituted-amino(phenyl) methylphosphonylacrylates (acrylamides) II. The products obtained in shorter reaction time with moderate yields are fully characterized by elemental analysis, IR, 1H, 13C, and 31P NMR spectral data. The role of introducing various substituents and the effect of incorporating a-aminophosphonates with an alkoxyethyl moiety into the parent cyanoacrylate (acrylamide) structure are investigated. Among the studied compounds, both II-17 and II-24 displayed good in vivo curative, protection, and inactivation effects, which were comparable to those of the commercial reference ningnanmycin (inhibitory rates of 58.8, 60.2, 78.9% and 60.0, 58.9, 85.5%, respectively, at 500 mg/L against TMV). To the best of the authors' knowledge, this is the first report on the synthesis and antiviral activity of the title compounds II.