181995-71-1Relevant articles and documents
Nitration of deactivated aromatic compounds via mechanochemical reaction
Wu, Jian-Wei,Zhang, Pu,Guo, Zhi-Xin
supporting information, (2021/05/05)
A variety of deactivated arenes were nitrated to their corresponding nitro derivatives in excellent yields under high-speed ball milling condition using Fe(NO3)3·9H2O/P2O5 as nitrating reagent. A radical involved mechanism was proposed for this facial, eco-friendly, safe, and effective nitration reaction.
Chemistry of the pyrrolo[1,2-a]benzimidazole antitumor agents: Influence of the 7-substituent on the ability to alkylate DNA and inhibit topoisomerase II
Zhou, Ru,Skibo, Edward B.
, p. 4321 - 4331 (2007/10/03)
This study addresses the influence the 7-substituent on the cytotoxicity of pyrrolo[1,2-a]benzimidazole quinones possessing a 6-aziridinyl group (PBIs) and a 6-acetamido group (APBIs). Reduction of a PBI to the aziridinyl hydroquinone results in both nucl