186093-87-8 Usage
Uses
Used in Pharmaceutical Industry:
2-(4-BROMOBENZOYL)-1-BENZOFURAN-5-CARBALDEHYDE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of molecules with therapeutic properties. Its structural features allow for the creation of complex molecules that can target specific biological pathways or receptors, potentially leading to new treatments for various diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(4-BROMOBENZOYL)-1-BENZOFURAN-5-CARBALDEHYDE is utilized as a precursor in the synthesis of bioactive compounds for crop protection and pest control. Its chemical properties enable the production of molecules that can effectively manage agricultural pests and diseases, thereby enhancing crop yields and quality.
Used in Material Science:
2-(4-BROMOBENZOYL)-1-BENZOFURAN-5-CARBALDEHYDE is employed as a component in the development of advanced materials with specific properties in material science. Its incorporation into material formulations can lead to the creation of substances with tailored characteristics, such as improved stability, reactivity, or selectivity, which can be applied in various technological and industrial processes.
Check Digit Verification of cas no
The CAS Registry Mumber 186093-87-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,0,9 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 186093-87:
(8*1)+(7*8)+(6*6)+(5*0)+(4*9)+(3*3)+(2*8)+(1*7)=168
168 % 10 = 8
So 186093-87-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H9BrO3/c17-13-4-2-11(3-5-13)16(19)15-8-12-7-10(9-18)1-6-14(12)20-15/h1-9H
186093-87-8Relevant articles and documents
Synthetic approaches to benzofuran containing Insulin Sensitivity Enhancer compounds for treatment of type II diabetes
Huff, Bret E.,Leffelman, Cindy L.,LeTourneau, Michael E.,Sullivan, Kevin A.,Ward, Jeffrey A.,Stille, John R.
, p. 1363 - 1384 (2007/10/03)
The search for Insulin Sensitivity Enhancer (ISE) compounds, for potential use in the treatment of Type II diabetes, has led to the synthesis of compounds that contain a benzofuran spacer between an aryloyl substituent and a 2,4-thiazolidinedione pharmacophore. Sequential combination of haloacetyl aryl substrates with 5-formylsalicylaldehyde gave the desired 2-aryloyl-5-formylbenzofuran intermediates. A related class of compounds, those with a methylene tether between the aromatic moiety and the benzofuran spacer, were also prepared through this strategy.
5-Formyl salicylaldehyde as a linker for the synthesis of benzofuran containing insulin sensitivity enhancer compounds
Stille, John R.,Ward, Jeffrey A.,Leffelman, Cindy,Sullivan, Kevin A.
, p. 9267 - 9270 (2007/10/03)
5-Formyl salicylaldehyde was prepared by treatment of 4-hydroxybenzaldehyde with HMTA in TFA. Reaction of this dialdehyde with α-haloacetyl aryl compounds gave 2,5-disubstituted benzofurans, from which an Insulin Sensitivity Enhancer compound was prepared.
