187669-28-9 Usage
Uses
Used in Pharmaceutical Industry:
4-Piperazin-1-yl-benzoic acid tert-butyl ester is used as a chemical intermediate for the synthesis of various drugs and pharmaceutical products. Its role in the development of medications is significant, particularly for the treatment of anxiety and related disorders, due to its inherent sedative and anxiolytic effects.
Used in Neuroscience Research:
In the field of neuroscience, 4-Piperazin-1-yl-benzoic acid tert-butyl ester is used as a research compound to explore its potential as a psychotropic drug. Its study contributes to the understanding of the compound's effects on the central nervous system and its possible applications in the treatment of neurological conditions.
Overall, 4-Piperazin-1-yl-benzoic acid tert-butyl ester's applications in both the pharmaceutical industry and medical research underscore its value as a key component in the development of new therapeutic agents and the advancement of scientific knowledge in the field of neuroscience.
Check Digit Verification of cas no
The CAS Registry Mumber 187669-28-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,6,6 and 9 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 187669-28:
(8*1)+(7*8)+(6*7)+(5*6)+(4*6)+(3*9)+(2*2)+(1*8)=199
199 % 10 = 9
So 187669-28-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H22N2O2/c1-15(2,3)19-14(18)12-4-6-13(7-5-12)17-10-8-16-9-11-17/h4-7,16H,8-11H2,1-3H3
187669-28-9Relevant articles and documents
Profiling small molecule inhibitors against helix-receptor interactions: The Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2
Porter, Jason R.,Helmers, Mark R.,Wang, Ping,Furman, Jennifer L.,Joy, Stephen T.,Arora, Paramjit S.,Ghosh, Indraneel
supporting information; experimental part, p. 8020 - 8022 (2011/01/03)
We validate a practical methodology for the rapid profiling of small molecule inhibitors of protein-protein interactions. We find that a well known BH3 family inhibitor can potently inhibit the p53/hDM2 interaction.
An efficient synthesis of ABT-263, a novel inhibitor of antiapoptotic Bcl-2 proteins
Wang, Guangjun,Zhang, Hushan,Zhou, Jing,Ha, Chengyong,Pei, Duanqing,Ding, Ke
experimental part, p. 2398 - 2404 (2009/04/07)
ABT-263, a newly developed Bcl-2 inhibitor, was efficiently synthesized. The key intermediates 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-enyl] methyl}piperazin-1-yl)benzoic acid and 4-fluoro-3-[(trifluoromethyl)sulfonyl] benzenesulfonamide were eff
