188879-36-9

Basic information

• Product Name: 1-Benzyl-4-(Pyridin-3-Yl)Piperidin-4-Ol
• Synonyms: 1-Benzyl-4-(Pyridin-3-Yl)Piperidin-4-Ol
• CAS NO: 188879-36-9
• Molecular Formula: C₁₇H₂₀N₂O
• Molecular Weight: 268.3535
• Mol File: 188879-36-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Benzyl-4-(Pyridin-3-Yl)Piperidin-4-Ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl-4-(Pyridin-3-Yl)Piperidin-4-Ol(188879-36-9)
• EPA Substance Registry System: 1-Benzyl-4-(Pyridin-3-Yl)Piperidin-4-Ol(188879-36-9)

Safety Data

• Hazardous Substances Data: 188879-36-9(Hazardous Substances Data)

Usage

Chemical Class

Piperidine derivative

Structure

Benzyl group at the first position
Piperidin-4-ol moiety at the fourth position
Pyridin-3-yl group at the fourth position

Usage

Research and development for medicinal and pharmaceutical purposes

Pharmacological Properties

Selective serotonin reuptake inhibitor (SSRI)
Potential to modulate neuronal activity

Specific Mechanisms of Action

Still being explored

Potential Therapeutic Applications

Still being explored

Upstream product

• 626-55-1 3-Bromopyridine 
• 3612-20-2 1-phenylmethyl-4-piperidone 

Downstream Products

• 188879-37-0 3-(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)pyridine 
• 50461-59-1 4-(pyridin-3-yl)piperidine-4-ol 
• 1191240-35-3 C₂₄H₃₃N₃O 

Relevant articles and documents

Substituted Disulfonamide Compounds

Substituted disulfonamide compounds corresponding to formula I: In which R1, R2, R3, R4a, R4b, R5a, R5b, R8, R9a, R9b, R10, R11, a, b, s, t and A have defined meanings, pharmaceutical compositions containing one or more such compounds, processes for preparing such compounds, and a method of using such compounds for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin receptor 1 (BR1).

Substituted Pyrimidine and Triazine Compounds

Substituted pyrimidine and triazine compounds corresponding to formula I wherein R1, R2, R3, R4a, R4b, R5a, R5b, R7, R8, R9a, R9b, R10, R11, A, a, b, s, t, V, W1, W2 and W3 have defined meanings, pharmaceutical compositions comprising such compounds, a process for preparing such compounds, and the use of such compounds and compositions to treat or inhibit pain and/or other disorders or disease states.

Substituted Indole Compounds

Substituted indole compounds corresponding to the formula I: In which R8, R9a, R9b, R10, R11, R200, R210, A, D, T, q, s and t have defined meanings, processes for the preparation thereof, pharmaceutical compositions containing such compounds and the use of substituted indole compounds for the treatment or inhibition of pain and other conditions which are at least partly mediated by Bradykinin 1 receptors (B1R).

SUBSTITUTED SULFONAMIDE COMPOUNDS

Substituted sulfonamide compounds corresponding to formula I processes for the preparation thereof, pharmaceutical compositions containing these compounds, and the use of such substituted sulfonamide compounds in pharmaceutical compositions for the treatment and/or inhibition of pain and other conditions at least partly mediated by the bradykinin 1 receptor

SUBSTITUTED SULFONAMIDE COMPOUNDS

Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.

Substituted Sulfonamide Compounds

Substituted sulfonamide compounds with bradykinin receptor (B1R) modulating activity; processes for the preparation thereof, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat or inhibit pain and/or other disorders and/or disease states.

Piperidine derivatives having renin inhibiting activity

Novel piperidine derivatives, their manufacture and use as medicaments, are disclosed. The invention is concerned with the novel piperidine derivatives of general formula I wherein R1, R2, R3, R4, Q, X, Z, m and n are as described herein.