194347-22-3

Basic information

• Product Name: Quinoline, 4-chloro-6-methyl-2-(2-nitrophenyl)-
• CAS NO: 194347-22-3
• Molecular Formula: C16H11ClN2O2
• Molecular Weight: 298.729
• Mol File: 194347-22-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Quinoline, 4-chloro-6-methyl-2-(2-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 4-chloro-6-methyl-2-(2-nitrophenyl)-(194347-22-3)
• EPA Substance Registry System: Quinoline, 4-chloro-6-methyl-2-(2-nitrophenyl)-(194347-22-3)

Safety Data

• Hazardous Substances Data: 194347-22-3(Hazardous Substances Data)

Upstream product

• 194347-21-2 6-methyl-2-(2-nitrophenyl)-4-quinolone 
• 610-14-0 2-nitrobenzyl chloride 
• 106-49-0 p-toluidine 
• 52119-39-8 ethyl (2-nitrobenzoyl)acetate 

Relevant articles and documents

A novel trifluoromethanesulfonamidophenyl-substituted quinoline derivative, GA 0113: Synthesis and pharmacological profiles

The trifluoromethanesulfonamidophenyl-substituted quinoline GA 0113 have been synthesized from o-nitrobenzoyl chloride via a multi-step process. GA 0113 displaced specific binding of [125I]-Sar1, Ile8-Ang II to AT1 receptors in membrane from Sf9 cells. In concious normotensive dogs, GA 0113 inhibited the Ang II-induced pressor response with ID50 of 0.032mg/kg and dose-dependently increased plasma renin activity for 48h.