1979-53-9

Basic information

• Product Name: Benzene, 1-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-4-methoxy-
• CAS NO: 1979-53-9
• Molecular Formula: C10H7F5O
• Molecular Weight: 238.157
• Mol File: 1979-53-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-4-methoxy-(1979-53-9)
• EPA Substance Registry System: Benzene, 1-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-4-methoxy-(1979-53-9)

Safety Data

• Hazardous Substances Data: 1979-53-9(Hazardous Substances Data)

Upstream product

• 711-38-6 4'-methoxy-2,2,2-trifluoroacetophenone 
• 1895-39-2 sodium chlorodifluoroacetate 
• 36029-83-1 α-(Chlordifluormethyl)-α-(trifluormethyl)-p-methoxybenzylchlorid 
• 431-49-2 2-bromo-1,1,3,3,3-pentafluoropropene 
• 696-62-8 para-iodoanisole 
• 58201-66-4 (bromodifluormethyl)triphenylphosphonium bromide 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 36087-08-8 α-(Chlordifluormethyl)-α-(trifluormethyl)-p-methoxy-benzylalkohol 
• 115262-00-5 [chloro(difluoro)methyl]trimethylsilane 

Downstream Products

• 1251579-65-3 (Z)-1,1-dibromo-3-(p-methoxyphenyl)-1,2,4,4,4-pentafluoro-2-butene 
• 29667-14-9 1-methoxy-4-(perfluoropropan-2-yl)benzene 
• 36029-70-6 3,3,3-trifluoro-2-(4'-methoxyphenyl)-1,1-diphenylpropene 

Relevant articles and documents

Metal Dehalogenation Route To Reactive Fluoroolefins

Metal dehalogenation of bromodifluoromethyltriphenylphosphonium bromide with Cd, Zn, or Hg provides a practical route to fluoroolefins that contain an allylic halogen or a pentafluorophenyl group.No SN2' or ring substituted products are observed.

Deoxygenative gem-difluoroolefination of carbonyl compounds with (chlorodifluoromethyl)trimethylsilane and triphenylphosphine

Background: 1,1-Difluoroalkenes cannot only be used as valuable precursors for organic synthesis, but also act as bioisosteres for enzyme inhibitors. Among various methods for their preparation, the carbonyl olefination with difluoromethylene phosphonium ylide represents one of the most straightforward methods. Results: The combination of (chlorodifluoromethyl)trimethylsilane (TMSCF2Cl) and triphenylphosphine (PPh3) can be used for the synthesis of gem-difluoroolefins from carbonyl compounds. Comparative experiments demonstrate that TMSCF2Cl is superior to (bromodifluoromethyl)trimethylsilane (TMSCF2Br) and (trifluoromethyl)trimethylsilane (TMSCF3) in this reaction. Conclusion: Similar to many other Wittig-type gem-difluoroolefination reactions in the presence of PPh3, the reaction of TMSCF2Cl with aldehydes and activated ketones is effective.