198543-64-5

Basic information

• Product Name: FMOC-D-ALPHA-T-BUTYLGLYCINE
• Synonyms: N-ALPHA-FMOC-D-T-BUTYLGLYCINE;N-ALPHA-FMOC-D-T-LEUCINE;N-ALPHA-FMOC-D-ALPHA-T-BUTYL-GLYCINE;N-ALPHA-T-FMOC-D-T-LEUCINE;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-T-BUTYLGLYCINE;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-T-LEUCINE;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-(R)-2-AMINO-3,3-DIMETHYL-BUTYRIC ACID;FMOC-D-ALPHA-T-BUTYLGLYCINE
• CAS NO: 198543-64-5
• Molecular Formula: C₂₁H₂₃NO₄
• Molecular Weight: 353.41
• Product Categories: Fluorenes, Flurenones;Amino Acids;Amino Acids & Deriv.;CHIRAL CHEMICALS;Peptide
• Mol File: 198543-64-5.mol

Chemical Properties

• Melting Point: 126-130°C
• Boiling Point: 554.1±33.0 °C(Predicted)
• Appearance: /
• Density: 1.209±0.06 g/cm3(Predicted)
• Storage Temp.: -15°C
• PKA: 3.92±0.10(Predicted)
• CAS DataBase Reference: FMOC-D-ALPHA-T-BUTYLGLYCINE(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-D-ALPHA-T-BUTYLGLYCINE(198543-64-5)
• EPA Substance Registry System: FMOC-D-ALPHA-T-BUTYLGLYCINE(198543-64-5)

Safety Data

• WGK Germany: WGK 2 water endangering
• HazardClass: IRRITANT
• Hazardous Substances Data: 198543-64-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
FMOC-D-ALPHA-T-BUTYLGLYCINE is used as a synthetic building block for the creation of peptide-based drugs. Its incorporation allows for the design of therapeutic peptides with specific biological activities, targeting a range of diseases and conditions.
Used in Research Applications:
In research settings, FMOC-D-ALPHA-T-BUTYLGLYCINE is utilized as a key component in the development of novel peptide sequences. It aids scientists in exploring the structure-function relationships of peptides and contributes to the advancement of peptide-based research.
Used in Industrial Peptide Production:
FMOC-D-ALPHA-T-BUTYLGLYCINE is employed as a crucial ingredient in the industrial synthesis of peptides. Its use enables the large-scale production of peptides with consistent quality and defined properties, catering to various commercial and medical needs.
Used in Diagnostics and Biochemical Assays:
FMOC-D-ALPHA-T-BUTYLGLYCINE is used as a reagent in diagnostic tests and biochemical assays. It helps in the detection and quantification of specific biomarkers, contributing to the accuracy and reliability of such assays.
Used in Cosmetics and Personal Care Industry:
In the cosmetics and personal care industry, FMOC-D-ALPHA-T-BUTYLGLYCINE is used as an active ingredient in peptide-based formulations. It is leveraged for its potential benefits in skin care, hair care, and other personal care products, aiming to enhance their efficacy and performance.

Downstream Products

• 268556-62-3 (R)-N-benzyl 2-amino-3,3-dimethylbutanamide 
• 268556-63-4 ((R)-1-Benzylcarbamoyl-2,2-dimethyl-propyl)-carbamic acid 4-nitro-phenyl ester 

Relevant articles and documents

Sterically biased 3,3-sigmatropic rearrangement of azides: Efficient preparation of nonracemic α-amino acids and heterocycles

(Chemical Equation Presented) Homochiral α-amino acids, heterocycles, and carbocycles are efficiently constructed via a short sequence of reactions starting from the chiral auxiliary p-menthane-3-carboxaldehyde. The key feature of the sequence is a highly selective tandem Mitsunobu/3,3-sigmatropic rearrangement of hydrazoic acid that procures enantiomerically enriched allylic azides. The sequence is either terminated by oxidative cleavage to provide amino acids or by ring-closing metathesis to provide heterocycles or carbocycles bearing nitrogen.