201334-88-5

Basic information

• Product Name: BOC-DL-TYR(2,6-DICHLORO-BZL)-OH
• Synonyms: BOC-O-2,6-DICHLOROBENZYL-DL-TYROSINE;BOC-DL-TYR(2,6-DICHLORO-BZL)-OH;BOC-DL-TYR(2,6-DI-CL-BZL)-OH;BOC-DL-TYROSINE(2,6-DICHLORO-BZL)-OH;BOC-DL-TYR(CL 2-BZL)-OH;N-ALPHA-T-BUTOXYCARBONYL-O-(2,6-DICHLOROBENZYL)-DL-TYROSINE;Boc-O-2,6-dichlorobenzyl-DL-tyrosine≥ 99% (TLC)
• CAS NO: 201334-88-5
• Molecular Formula: C21H23Cl2NO5
• Molecular Weight: 440.32
• Mol File: 201334-88-5.mol

Chemical Properties

• Boiling Point: 594.0±50.0 °C(Predicted)
• Appearance: /
• Density: 1.305±0.06 g/cm3(Predicted)
• Storage Temp.: Store at RT.
• PKA: 2.98±0.10(Predicted)
• CAS DataBase Reference: BOC-DL-TYR(2,6-DICHLORO-BZL)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-DL-TYR(2,6-DICHLORO-BZL)-OH(201334-88-5)
• EPA Substance Registry System: BOC-DL-TYR(2,6-DICHLORO-BZL)-OH(201334-88-5)

Safety Data

• Hazardous Substances Data: 201334-88-5(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 40298-69-9 4-(2,6-dichlorobenzyloxy)-L-phenylalanine 
• 85842-19-9 N-tert-Butoxycarbonyl-O-2,6-dichlorbenzyl-(S)-tyrosin Methylester 

Downstream Products

• 101697-62-5 4-ε-2-chlorobenzyloxycarbonyl)-L-tyrosyl(O-2,6-dichlorobenzyl)-L-alanyloxy>-6-mercaptodibenzofuran 
• 127272-73-5 Boc-Tyr(Cl₂Bzl)-Gln-Lys(z)-Arg(Mts)-OMe 
• 123196-92-9 Boc-Tyr(Cl₂-Bzl)-OBt 
• 85842-19-9 N-tert-Butoxycarbonyl-O-2,6-dichlorbenzyl-(S)-tyrosin Methylester 
• 79985-48-1 Dynorphin A-(1-11) amide 
• 207613-94-3 Ac-Tyr-Ile-Gly-Ser-Arg-β-Ala-OH 

Relevant articles and documents

Synthesis and biological activity of N-substituted aminocarbonyl-1,3- dioxolanes as VLA-4 antagonists

A novel set of compounds with a 1,3-dioxolane ring which acts as a proline bioisostere have been successfully designed as VLA-4 receptor antagonists. Compounds (18e), (28j), and (35g) were shown to have high receptor affinities.

A simple method for the alkaline hydrolysis of esters

A very mild and rapid procedure for the efficient alkaline hydrolysis of esters in non-aqueous conditions has been developed, by the use of dichloromethane/methanol (9:1) as solvent. This method conveniently provides both carboxylic acids and alcohols from the corresponding esters and sodium hydroxide in a few minutes at room temperature. A plausible reaction mechanism is proposed.