20172-33-2

Basic information

• Product Name: Hexanamide, N-(4-methylphenyl)-
• CAS NO: 20172-33-2
• Molecular Formula: C13H19NO
• Molecular Weight: 205.3
• Mol File: 20172-33-2.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Hexanamide, N-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanamide, N-(4-methylphenyl)-(20172-33-2)
• EPA Substance Registry System: Hexanamide, N-(4-methylphenyl)-(20172-33-2)

Safety Data

• Hazardous Substances Data: 20172-33-2(Hazardous Substances Data)

Upstream product

• 6393-56-2 pentylmagnesium chloride 
• 622-58-2 p-Tolylisocyanate 
• 2051-49-2 n-hexanoic anhydride 
• 501-60-0 1,2-di(p-tolyl)diazene 
• 927-49-1 dipentyl ketone 
• 726-42-1 di-p-tolylcarbodiimide 
• 628-02-4 Caproamide 
• 624-31-7 4-tolyl iodide 
• 180071-98-1 1-(p-tolyl)-1-hexyne 
• 106-49-0 p-toluidine 
• 142-61-0 Hexanoyl chloride 
• 106-38-7 para-bromotoluene 
• 144357-66-4 8-(N-(n-hexanoyl)amino)quinoline 
• 99-99-0 1-methyl-4-nitrobenzene 

Relevant articles and documents

Efficient nitriding reagent and application thereof

The invention discloses an efficient nitriding reagent and application thereof, wherein the nitriding reagent comprises nitrogen oxide, an active agent, a reducing agent and an organic solvent. By applying the nitriding reagent, nitrogen-containing compounds such as amide, nitrile and the like can be produced, and the method is simple in condition, low in waste discharge amount and simple in reaction equipment.

Nitromethane as a nitrogen donor in Schmidt-type formation of amides and nitriles

The Schmidt reaction has been an efficient and widely used synthetic approach to amides and nitriles since its discovery in 1923. However, its application often entails the use of volatile, potentially explosive, and highly toxic azide reagents. Here, we report a sequence whereby triflic anhydride and formic and acetic acids activate the bulk chemical nitromethane to serve as a nitrogen donor in place of azides in Schmidt-like reactions. This protocol further expands the substrate scope to alkynes and simple alkyl benzenes for the preparation of amides and nitriles.

N-Acyl-N-(4-chlorophenyl)-4-nitrobenzenesulfonamides: Highly selective and efficient reagents for acylation of amines in water

A variety of N-acyl-N-(4-chlorophenyl)-4-nitrobenzenesulfonamides (1a-e) were synthesized in one pot from 4-chloroaniline under solvent-free conditions and have been developed as chemoselective N-acylation reagents. Selective protection of primary amines in the presence of secondary amines, acylation of aliphatic amines in the presence of aryl amines, and monofunctionalization of primary-secondary diamines as well as selective N-acylation of amino alcohols using these reagents are described. All of the acylation reactions were carried out in water as a green solvent. High stability and easy preparation of these acylating reagents are other advantages of this method.