205647-25-2Relevant articles and documents
Enantioselective addition of thiazolyllithium to aldimines with the aid of chiral ligand. Asymmetric synthesis of (S)-DOE, a component of marine natural product, dolastatin 10
Tomioka, Kiyoshi,Satoh, Maki,Taniyama, Daisuke,Kanai, Motomu,Iida, Akira
, p. 77 - 80 (1998)
The external chiral ligand mediated asymmetric reaction of thiazolyllithium with aldimines was examined. The amino ether (5) gave rise to relatively high selectivity in the reaction of phenylimine, and sparteine (6) provided high selectivity in the reacti