20734-66-1

Basic information

• Product Name: 3-Amino-1,2-benzenediol
• Synonyms: 3-Amino-1,2-benzenediol;1,2-Benzenediol, 3-aMino-;3-aMinobenzene-1,2-diol
• CAS NO: 20734-66-1
• Molecular Formula: C₆H₇NO₂
• Molecular Weight: 125
• Mol File: 20734-66-1.mol

Chemical Properties

• Melting Point: 142-145 °C
• Boiling Point: 297.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.412±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 9.59±0.10(Predicted)
• CAS DataBase Reference: 3-Amino-1,2-benzenediol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-1,2-benzenediol(20734-66-1)
• EPA Substance Registry System: 3-Amino-1,2-benzenediol(20734-66-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 20734-66-1(Hazardous Substances Data)

Usage

Uses

Used in Dye Production:
3-Amino-1,2-benzenediol is used as a chemical intermediate for the production of certain types of dyes. Its unique chemical structure allows it to be a key component in the synthesis of various dye molecules, contributing to their color and stability.
Used in Pharmaceutical Industry:
3-Amino-1,2-benzenediol is used as a building block in the synthesis of pharmaceuticals. Its presence in the molecular structure of certain drugs can influence their biological activity, making it a valuable compound in the development of new medications.
Used in Agrochemicals:
3-Amino-1,2-benzenediol is used as a raw material in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties enable it to be incorporated into the formulation of these products, enhancing their effectiveness in controlling pests and weeds in agricultural settings.

Upstream product

• 60-29-7 diethyl ether 
• 34529-06-1 dimethyl 3-aminophthalate 
• 1334660-40-0 ethyl 2,3-bis(benzyloxy)phenylcarbamate 
• 2411-83-8 methyl-2,3-dihydroxybenzoate 
• 303-38-8 2,3-Dihydroxybenzoic acid 
• 74272-78-9 2,3-dibenzyloxybenzoic acid 
• 2169-27-9 Methyl 2,3-bis(benzyloxy)benzoate 
• 6665-98-1 3-nitrobenzene-1,2-diol 

Downstream Products

• 258532-76-2 8-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazine 
• 94242-04-3 7-hydroxybenzoxazole 
• 942589-90-4 2-(4-bromophenyl)-1,3-benzoxazol-7-ol 

Relevant articles and documents

Identification of novel matrix metalloproteinase inhibitors by screening of phenol fragments library

In the last 20 years, a great variety of synthetic, low molecular weight MMP inhibitors (MMPIs) have been synthesized and tested, although none has reached clinical utility. Exploration of novel ZBGs and development of non-hydroxamate MMPI has become a focus in current research. It's well-known that polyphenols can produce beneficial effects on human health by their antioxidant properties as well as they have the ability to block gelatinase activity. In this work we tested a series of selected phenols as MMP inhibitors. The most interesting hit (B6) shows sub-micromolar activity against MMP-2 (IC50 0.59 ± 0.05 μM, LE = 1.07) and a fairly good selectivity spectrum. A screening of selected phenols against four matrix metalloproteinases is reported. Eight phenols showed a very interesting activity and selective profile. The most interesting hit (B6) presents a sub-micromolar activity against MMP-2 (IC50 0.59±0.05μM). Copyright

Benzimidazole compounds as bradykinin antagonists

PCT No. PCT/JP95/01478 Sec. 371 Date Feb. 3, 1997 Sec. 102(e) Date Feb. 3, 1997 PCT Filed Jul. 25, 1995 PCT Pub. No. WO96/04251 PCT Pub. Date Feb. 15, 1996This invention relates to a heterocyclic compound of the formula: wherein a group of the formula: is a group of the formula: etc., X is O, S or N-R5, R1 is lower alkyl, etc., R5 is hydrogen, lower alkyl, etc., R2 is hydrogen, halogen, lower alkyl, etc., R3 is halogen, lower alkyl, etc., R4 is amino optionally having suitable substituent(s), and A is lower alkylene, and a salt thereof, to processes for preparation thereof, and to a pharmaceutical composition comprising the same for the prevention and/or the treatment of bradykinin or its analogues mediated diseases in human being or animals.