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5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE is a derivative of 8-Oxo-2'-deoxyguanosine (O850250), a compound that serves as a marker for DNA damage linked to mutagenesis and carcinogenesis. This molecule has the potential to induce differentiation in Friend murine erythroleukemia cells in vitro, making it a significant compound in the field of molecular biology and cancer research.

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  • 2-(Benzylamino)-9-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one

    Cas No: 209785-64-8

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  • 9-[(2R,4S,5R)-5-[[(2,3-dimethoxyphenyl)-diphenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-2-(ethylamino)-3H-purin-6-one

    Cas No: 209785-64-8

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  • 209785-64-8 Structure
  • Basic information

    1. Product Name: 5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE
    2. Synonyms: 5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE;5'-O-(DMT)-N2-ETHYL-2'-DEOXYGUANOSINE
    3. CAS NO:209785-64-8
    4. Molecular Formula: C38H37N5O6
    5. Molecular Weight: 597.66
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 209785-64-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE(209785-64-8)
    11. EPA Substance Registry System: 5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE(209785-64-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 209785-64-8(Hazardous Substances Data)

209785-64-8 Usage

Uses

Used in Molecular Biology Research:
5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE is used as a research tool for studying the effects of DNA damage on cellular processes, particularly in the context of mutagenesis and carcinogenesis. Its ability to induce differentiation in specific cell lines makes it a valuable asset in understanding the mechanisms behind these processes and potentially developing targeted therapies.
Used in Cancer Research:
In the field of cancer research, 5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE is used as a compound to investigate the differentiation of cancer cells, specifically Friend murine erythroleukemia cells. This application aims to explore the potential of this molecule in developing novel therapeutic strategies for cancer treatment, focusing on the modulation of cellular differentiation pathways.
Used in Drug Development:
5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE may also be utilized in the development of new drugs targeting DNA damage and cancer cell differentiation. Its unique properties and interactions with cellular processes make it a promising candidate for the creation of targeted therapies that could potentially improve patient outcomes in cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 209785-64-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,9,7,8 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 209785-64:
(8*2)+(7*0)+(6*9)+(5*7)+(4*8)+(3*5)+(2*6)+(1*4)=168
168 % 10 = 8
So 209785-64-8 is a valid CAS Registry Number.

209785-64-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 9-[(2R,4S,5R)-5-[[(2,3-dimethoxyphenyl)-diphenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-2-(ethylamino)-3H-purin-6-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:209785-64-8 SDS

209785-64-8Downstream Products

209785-64-8Relevant articles and documents

N2- and C8-substituted oligodeoxynucleotides with enhanced thrombin inhibitory activity in vitro and in vivo.

He,Krawczyk,Swaminathan,Shea,Dougherty,Terhorst,Law,Griffin,Coutre,Bischofberger

, p. 2234 - 2242 (2007/10/03)

2'-Deoxyguanosine (G) analogues carrying various hydrophobic substituents in the N2 and C8 positions were synthesized and introduced through solid-phase synthesis into 15-mer oligodeoxynucleotide, GGTTGGTGTGGTTGG, which forms a chairlike structure consist

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