209785-64-8 Usage
Uses
Used in Molecular Biology Research:
5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE is used as a research tool for studying the effects of DNA damage on cellular processes, particularly in the context of mutagenesis and carcinogenesis. Its ability to induce differentiation in specific cell lines makes it a valuable asset in understanding the mechanisms behind these processes and potentially developing targeted therapies.
Used in Cancer Research:
In the field of cancer research, 5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE is used as a compound to investigate the differentiation of cancer cells, specifically Friend murine erythroleukemia cells. This application aims to explore the potential of this molecule in developing novel therapeutic strategies for cancer treatment, focusing on the modulation of cellular differentiation pathways.
Used in Drug Development:
5'-O-(DIMETHOXYTRITYL)-N2-ETHYL-2'-DEOXYGUANOSINE may also be utilized in the development of new drugs targeting DNA damage and cancer cell differentiation. Its unique properties and interactions with cellular processes make it a promising candidate for the creation of targeted therapies that could potentially improve patient outcomes in cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 209785-64-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,9,7,8 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 209785-64:
(8*2)+(7*0)+(6*9)+(5*7)+(4*8)+(3*5)+(2*6)+(1*4)=168
168 % 10 = 8
So 209785-64-8 is a valid CAS Registry Number.
209785-64-8Relevant articles and documents
N2- and C8-substituted oligodeoxynucleotides with enhanced thrombin inhibitory activity in vitro and in vivo.
He,Krawczyk,Swaminathan,Shea,Dougherty,Terhorst,Law,Griffin,Coutre,Bischofberger
, p. 2234 - 2242 (2007/10/03)
2'-Deoxyguanosine (G) analogues carrying various hydrophobic substituents in the N2 and C8 positions were synthesized and introduced through solid-phase synthesis into 15-mer oligodeoxynucleotide, GGTTGGTGTGGTTGG, which forms a chairlike structure consist