214068-96-9

Basic information

• Product Name: Octanoic acid (S)-2-(benzyloxy-diisopropylamino-phosphanyloxy)-1-octanoyloxymethyl-ethyl ester
• Synonyms: Octanoic acid (S)-2-(benzyloxy-diisopropylamino-phosphanyloxy)-1-octanoyloxymethyl-ethyl ester
• CAS NO: 214068-96-9
• Molecular Weight: 581.773
• Mol File: 214068-96-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Octanoic acid (S)-2-(benzyloxy-diisopropylamino-phosphanyloxy)-1-octanoyloxymethyl-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Octanoic acid (S)-2-(benzyloxy-diisopropylamino-phosphanyloxy)-1-octanoyloxymethyl-ethyl ester(214068-96-9)
• EPA Substance Registry System: Octanoic acid (S)-2-(benzyloxy-diisopropylamino-phosphanyloxy)-1-octanoyloxymethyl-ethyl ester(214068-96-9)

Safety Data

• Hazardous Substances Data: 214068-96-9(Hazardous Substances Data)

Upstream product

• 214068-80-1 Octanoic acid (R)-2-(4-methoxy-benzyloxy)-1-octanoyloxymethyl-ethyl ester 
• 128753-68-4 (benzyloxy)chloro(diisopropylamino)phosphane 
• 113973-38-9 sn-2,3-dioctanoylglycerol 

Downstream Products

• 796883-90-4 Octanoic acid (S)-2-{benzyloxy-[(1R,2S,3S,4R,5R,6S)-2,4,6-tris-benzyloxy-3-(bis-benzyloxy-phosphoryloxy)-5-hydroxy-cyclohexyloxy]-phosphoryloxy}-1-octanoyloxymethyl-ethyl ester 

Relevant articles and documents

Asymmetric Total Synthesis of Phosphatidylinositol 3-Phosphate and 4-Phosphate Derivatives

New asymmetric syntheses of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 4-phosphate (PtdIns(4)P) derivatives are described. Key intermediates were used to prepare diacylglyceryl moieties with dibutyryl, dioctanoyl, and dihexadecanoyl chains. In addition, a modified route provided PtdIns(3)P and PtdIns(4)P triesters with P-1-linked aminopropyl groups for preparation of affinity probes. The synthesis of the inosityl precursor employed a dibutyltin oxide-mediated p-methoxybenzyl (PMB) etherification to give either the 2-PMB- or the 3-PMB-protected glucopyranosides. The Ferrier rearrangement was used to convert suitably protected glucose derivatives to enantiomerically pure, differentially protected D-myo-inositol key intermediates. A versatile phosphoramidite reagent was employed to allow synthesis of PtdInsPn derivatives with diacylglyceryl moieties of different chain lengths.