214422-55-6Relevant articles and documents
A versatile and stereoselective synthesis of (±)-epibatidine
Avenoza,Busto,Cativiela,Peregrina
, p. 1335 - 1338 (1998)
A new synthesis of (±)-epibatidine has been achieved, involving a Diels-Alder cycloaddition of (Z)-4-[5'-(2'-chloropyridylmethylene)]-2-phenyl-5(4H)-oxazolone with Danishefsky's diene, and an intramolecular nucleophilic displacement in a trans-1,4-methanesulfonyloxycyclohexylamide derivative as key steps.