218449-31-1

Basic information

• Product Name: Methyl 2-aMino-2-(3,4-difluorophenyl)acetate
• Synonyms: Methyl 2-aMino-2-(3,4-difluorophenyl)acetate
• CAS NO: 218449-31-1
• Molecular Formula: C₉H₉F₂NO₂
• Molecular Weight: 201.1700664
• Mol File: 218449-31-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 2-aMino-2-(3,4-difluorophenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-aMino-2-(3,4-difluorophenyl)acetate(218449-31-1)
• EPA Substance Registry System: Methyl 2-aMino-2-(3,4-difluorophenyl)acetate(218449-31-1)

Safety Data

• Hazardous Substances Data: 218449-31-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 218449-30-0 amino-(3,4-difluorophenyl)-acetonitrile 

Downstream Products

• 277295-93-9 2-amino-2-(3,4-difluorophenyl)-ethanol 
• 277295-97-3 1-(3,4-difluorophenyl)-2-methyl-2-hydroxypropylamine 
• 218451-28-6 (+)-3-(3-(4-cyano-4-(2,4-dichloro)phenylpiperidin-1-yl)propyl)aminocarbonyl-4-(3,4-difluorophenyl)-2-oxazolidinone 
• 218451-40-2 (+)-3-(3-(4-Aminocarbonyl-4-(4-chloro)phenylpiperidin-1-yl)-propyl)aminocarbonyl-4-(3,4-difluoro)phenyl-2-oxazolidinone 
• 218449-37-7 4-(3,4-difluorophenyl)-2-oxo-oxazolidine-3-carboxylic acid-4-nitro-phenyl ester 
• 218450-42-1 4-(3,5-difluorophenyl)-5,5-dimethyl-2-oxo-oxazolidine 
• 218449-35-5 [1-(3,4-difluorophenyl)-2-hydroxy-ethyl]-carbamic acid-tert-butyl ester 
• 225641-91-8 4-(3,4-difluorophenyl)-2-oxazolidinone 

Relevant articles and documents

SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS

This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therepeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier.

MORPHOLINONE AND MORPHOLINE DERIVATIVES AND USES THEREOF

This invention is directed to morpholinone and morpholine derivatives which are selective antagonists for human α 1a receptors. This invention is also related to uses of these compounds for lowering intraocular pressure, inhibiting cholesterol synthesis, relaxing lower urinary tract tissue, the treatment of benign prostatic hyperplasia, impotency, cardiac arrhythmia, sympathetic mediated pain, migraine, and for the treatment of any disease where the antagonism of the α 1a receptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.

Oxazolidinones as alpha 1A receptor antagonists

This invention is directed to oxazolidinone compounds which are selective antagonists for human alpha 1A receptors. This invention is also related to uses of these compounds for lowering intraocular pressure, inhibiting cholesterol synthesis, relaxing lower urinary tract tissue, the treatment of benign prostatic hyperplasia, impotency, cardiac arrhythmia and for the treatment of any disease where the antagonism of the alpha 1A receptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.