220499-13-8

Basic information

• Product Name: tert-butyl 4-(bromomethyl)-1H-indole-1-carboxylate
• Synonyms: tert-butyl 4-(bromomethyl)-1H-indole-1-carboxylate;tert-Butyl 4-(bromomethyl)indole-1-carboxylate;1H-Indole-1-carboxylic acid, 4-(broMoMethyl)-, 1,1-diMethylethyl ester
• CAS NO: 220499-13-8
• Molecular Formula: C₁₄H₁₆BrNO₂
• Molecular Weight: 310.2
• Mol File: 220499-13-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-butyl 4-(bromomethyl)-1H-indole-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(bromomethyl)-1H-indole-1-carboxylate(220499-13-8)
• EPA Substance Registry System: tert-butyl 4-(bromomethyl)-1H-indole-1-carboxylate(220499-13-8)

Safety Data

• Hazardous Substances Data: 220499-13-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Tert-butyl 4-(bromomethyl)-1H-indole-1-carboxylate is used as a reagent in organic synthesis for the introduction of the indole moiety into various molecules. Its unique structure allows for the creation of a wide range of indole-containing compounds, which are important in many chemical and pharmaceutical applications.
Used in Pharmaceutical and Agrochemical Synthesis:
tert-butyl 4-(bromomethyl)-1H-indole-1-carboxylate serves as a precursor for the synthesis of pharmaceuticals and agrochemicals. Its ability to be incorporated into complex molecules makes it a useful building block in the development of new drugs and agricultural products.
Used in Medicinal Chemistry and Drug Discovery:
Due to its structural features and reactivity, tert-butyl 4-(bromomethyl)-1H-indole-1-carboxylate may have potential applications in medicinal chemistry and drug discovery. Researchers can leverage its properties to design and synthesize new compounds with therapeutic potential or to improve the efficacy of existing drugs.

Upstream product

• 1313237-54-5 1-(tert-butyl) 4-methyl indoline-1,4-dicarboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 220499-11-6 1-(tert-butyl) methyl 1H-1,4-indoledicarboxylate 
• 73816-11-2 Methyl trans-2-<β-(dimethylamino)vinyl>-3-nitrobenzoate 
• 1975-50-4 2-methyl-3-nitrobenzic acid 
• 59382-59-1 2-methyl-3-nitro-benzoic acid methyl ester 
• 39830-66-5 methyl 1H-indole-4-carboxylate 
• 220499-12-7 tert-butyl 4-(hydroxymethyl)-1H-1-indolecarboxylate 

Downstream Products

• 1352873-93-8 N-{5-chloro-4'-[2-cyclopropylimino-3-(1H-indol-4-ylmethyl)-2,3-dihydro-benzoimidazol-1-yl]-biphenyl-2-yl}-acetamide 
• 1352873-16-5 N-{5-chloro-4'-[2-imino-3-(1H-indol-4-ylmethyl)-2,3-dihydro-benzoimidazol-1-yl]-biphenyl-2-yl}-acetamide 
• 1352874-54-4 4-[2-[(E)-tert-butoxycarbonylimino]-3-(2'-carboxy-5'-chloro-biphenyl-4-yl)-2,3-dihydro-benzoimidazol-1-ylmethyl]-indole-1-carboxylic acid tert-butyl ester 
• 1352873-26-7 6-acetylamino-4'-[2-imino-3-(1H-indol-4-ylmethyl)-2,3-dihydro-benzoimidazol-1-yl]-biphenyl-3-carboxylic acid dimethylamide 
• 1352873-28-9 N-(6-chloro-2-{4-[2-imino-3-(1H-indol-4-ylmethyl)-2,3-dihydro-benzoimidazol-1-yl]-phenyl}-pyridin-3-yl)-acetamide 
• 1352873-29-0 N-(5-chloro-3-{4-[2-imino-3-(1H-indol-4-ylmethyl)-2,3-dihydro-benzoimidazol-1-yl]-phenyl}-pyridin-2-yl)-acetamide 
• 1352874-32-8 4-{3-(4-bromo-phenyl)-2-[(E)-tert-butoxycarbonylimino]-2,3-dihydro-benzoimidazol-1-ylmethyl}-indole-1-carboxylic acid tert-butyl ester 
• 1352874-34-0 4-[3-(4-Dihydroxyboronyl-phenyl)-2-imino-2,3-dihydro-benzoimidazol-1-ylmethyl]-indole-1-carboxylic acid tert-butyl ester 
• 1352873-77-8 N-(4-chloro-2-{5-[2-imino-3-(1H-indol-4-ylmethyl)-2,3-dihydro-benzoimidazol-1-yl]-pyridin-2-yl}-phenyl)-acetamide 
• 1352873-82-5 N-(4-chloro-2-{5-[6-fluoro-2-imino-3-(1H-indol-4-ylmethyl)-2,3-dihydro-benzoimidazol-1-yl]-pyridin-2-yl}-phenyl)-acetamide 
• 1352874-01-1 N-{5-chloro-4'-[6-fluoro-2-imino-3-(1H-indol-4-ylmethyl)-2,3-dihydro-benzoimidazol-1-yl]-biphenyl-2-yl}-acetamide 
• 1352874-64-6 4-[3-(2'-acetylamino-5'-chloro-biphenyl-4-yl)-5-fluoro-2-imino-2,3-dihydro-benzoimidazol-1-ylmethyl]-indole-1-carboxylic acid tert-butyl ester 
• 1352874-06-6 N-{5-chloro-4'-[7-chloro-2-imino-3-(1H-indol-4-ylmethyl)-2,3-dihydro-benzoimidazol-1-yl]-biphenyl-2-yl}-acetamide 
• 1352874-27-1 4-[3-(4-bromo-phenyl)-2-imino-2,3-dihydro-benzoimidazol-1-ylmethyl]-indole-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

PIPERIDINYL SUBSTITUTED 1,3-DIHYDRO-BENZOIMIDAZOL-2-YLIDENEAMINE DERIVATIVES

The invention relates to new derivatives of formula (I) wherein the substituents are as defined in the specification; to processes for the preparation of such derivatives; pharmaceutical compositions comprising such derivatives; such derivatives as a medicament; such derivatives for the treatment of one or more IGF-1R mediated disorders or diseases

BIPHENYL SUBSTITUTED 1,3-DIHYDRO-BENZOIMIDAZOL-2-YLIDENEAMINE DERIVATIVES

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Neo-tryptophan

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