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  • OLANZAPINE PAMOATE; OLANZAPINE PAMOATE [USAN];10H-THIENO(2,3-B)(1,5)BENZODIAZEPINE, 2-METHYL-4-(4-METHYL-1-PIPERAZINYL)-, 4,4'-METHLENEBIS(3-HYDROXY-2-NAPHTHALENECARBOXYLATE) (1:1), MONOHYDRATE;2-METH

    Cas No: 221373-18-8

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  • Afine Chemicals Limited
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  • 221373-18-8 Structure
  • Basic information

    1. Product Name: Olanzapine Pamoate Hydrate
    2. Synonyms: Olanzapine Pamoate Hydrate;2-Methyl-4-(4-Methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylate] Monohydrate;4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid coMpound with 2-Methyl-4-(4-Methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine Hydrate
    3. CAS NO:221373-18-8
    4. Molecular Formula: C40H38N4O7S
    5. Molecular Weight: 718.81732
    6. EINECS: N/A
    7. Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
    8. Mol File: 221373-18-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Olanzapine Pamoate Hydrate(CAS DataBase Reference)
    10. NIST Chemistry Reference: Olanzapine Pamoate Hydrate(221373-18-8)
    11. EPA Substance Registry System: Olanzapine Pamoate Hydrate(221373-18-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 221373-18-8(Hazardous Substances Data)

221373-18-8 Usage

Uses

A new Olanzapine pamoate formulation of a second-generation antipsychotic

Check Digit Verification of cas no

The CAS Registry Mumber 221373-18-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,1,3,7 and 3 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 221373-18:
(8*2)+(7*2)+(6*1)+(5*3)+(4*7)+(3*3)+(2*1)+(1*8)=98
98 % 10 = 8
So 221373-18-8 is a valid CAS Registry Number.

221373-18-8Downstream Products

221373-18-8Relevant articles and documents

A PROCESS FOR PREPARATION OF OLANZAPINE PAMOATE

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Page/Page column 8, (2014/09/03)

An improved process for preparation of Olanzapine pamoate monohydrate from Olanzpaine is disclosed which comprises mixing at room temperature a solution of olanzapine prepared in water in presence of an acid, with a solution of pamoic acid prepared in water in presence of a base; stirring and maintaining the reaction mixture for a sufficient time till precipitation of solid and drying the solid to obtain olazapine pamoate monohydrate

OLANZAPINE PAMOATE DIHYDRATE

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Page/Page column 7, (2008/06/13)

The present invention relates olanzapine pamoate dihydrate, pharmaceutical compositions thereof and use in treating certain mental disorders, such as schizophrenia. X-16133

2-methyl-thieno-benzodiazepine formulation

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, (2008/06/13)

The invention provides a pharmaceutically acceptable oleaginous or cholesterol microsphere formulation of olanzapine or olanzapine pamoate or solvates thereof. The invention further provides novel olanzapine pamoate salts or solvates thereof.

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