224178-65-8

Basic information

• Product Name: 4-(4-piperidinyloxy)pyridine(SALTDATA: 2HCl)
• Synonyms: 4-(4-piperidinyloxy)pyridine(SALTDATA: 2HCl);4-(piperidin-4-yloxy)pyridine;4-(Pyridin-4-yloxy)piperidine;4-(4-piperidinyloxy)pyridine
• CAS NO: 224178-65-8
• Molecular Formula: C₁₀H₁₄N₂O
• Molecular Weight: 178.23096
• Mol File: 224178-65-8.mol

Chemical Properties

• Boiling Point: 301.8±32.0 °C(Predicted)
• Appearance: /
• Density: 1.078±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 9.47±0.10(Predicted)
• CAS DataBase Reference: 4-(4-piperidinyloxy)pyridine(SALTDATA: 2HCl)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-piperidinyloxy)pyridine(SALTDATA: 2HCl)(224178-65-8)
• EPA Substance Registry System: 4-(4-piperidinyloxy)pyridine(SALTDATA: 2HCl)(224178-65-8)

Safety Data

• Hazardous Substances Data: 224178-65-8(Hazardous Substances Data)

Upstream product

• 4727-72-4 1-benzyl-4-hydroxypiperidine 
• 7379-35-3 4-chlorpyridine hydrochloride 
• 900511-91-3 4-[(1-benzylpiperidin-4-yl)oxy]-pyridine 
• 626-64-2 pyridin-4-ol 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 

Downstream Products

• 1400691-96-4 C₁₈H₁₈N₄O₂ 
• 1400691-81-7 N-[2-fluoro-5-(trifluoromethyl)phenyl]-1-methyl-3-[4-(4-pyridinyloxy)-1-piperidinyl]-1H-1,2,4-triazol-5-amine 
• 1187522-78-6 4-[1-(4-bromophenyl)piperidin-4-yloxy]pyridine 
• 1208254-13-0 N-(5-tert-butyl-2-methylphenyl)-7-methyl-2-[4-(pyridin-4-yloxy)piperidin-1-yl]-7H-purin-6-amine 

Relevant articles and documents

DRUG COMBINATIONS CONTAINING PDE4 INHIBITORS AND NSAIDS

The present invention relates to new drug combinations which contain in addition to one or more PDE4-inhibitors at least one NSAID (=non-steroidal anti-inflammatory drug) (2), processes for preparing them and their use in treating in particular respiratory complaints such as for example COPD, chronic sinusitis and asthma. The invention particularly relates to those drug combinations which contain, in addition to one or more, preferably one PDE4 inhibitor of general formula 1 wherein X is SO or SO2, but preferably SO, and wherein R1, R2, R3 and R4 have the meanings given in claim 1, at least one NSAID (2), the preparation thereof and the use thereof for the treatment of respiratory complaints.

NOVEL SUBSTITUTED TRIAZOLYL PIPERAZINE AND TRIAZOLYL PIPERIDINE DERIVATIVES AS GAMMA SECRETASE MODULATORS

The present invention is concerned with novel substituted triazolyl piperazine and triazolyl piperidine derivatives of Formula (I) wherein R1, R2, R3, R4a, R4b, R5, X, Y1, Y

Substituted Pyrimidine and Triazine Compounds

Substituted pyrimidine and triazine compounds corresponding to formula I wherein R1, R2, R3, R4a, R4b, R5a, R5b, R7, R8, R9a, R9b, R10, R11, A, a, b, s, t, V, W1, W2 and W3 have defined meanings, pharmaceutical compositions comprising such compounds, a process for preparing such compounds, and the use of such compounds and compositions to treat or inhibit pain and/or other disorders or disease states.

Substituted triazole derivatives as oxytocin antagonists

The present invention relates to substituted triazoles of formula (I), uses thereof, processes for the preparation thereof and compositions containing said compounds. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction.