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Ethanone, 1-[4-(dimethylamino)-3-pyridinyl]-2,2,2-trifluoro(9CI), also known as 1-(4-(dimethylamino)-3-pyridin-3-yl)-2,2,2-trifluoroethan-1-one, is a chemical compound with the molecular formula C10H11F3N2O. It is a fluorinated ketone featuring a pyridine ring and a dimethylamino group attached. Ethanone, 1-[4-(dimethylamino)-3-pyridinyl]-2,2,2-trifluoro(9CI) is recognized for its versatile reactivity and functional groups, making it a valuable building block in organic synthesis and a common intermediate in the synthesis of pharmaceuticals and agrochemicals. Its unique chemical properties and structure have also attracted interest in the field of medicinal chemistry for potential applications.

230305-72-3

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  • Ethanone, 1-[4-(dimethylamino)-3-pyridinyl]-2,2,2-trifluoro- (9CI)

    Cas No: 230305-72-3

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230305-72-3 Usage

Uses

Used in Pharmaceutical Synthesis:
Ethanone, 1-[4-(dimethylamino)-3-pyridinyl]-2,2,2-trifluoro(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with improved efficacy and selectivity. Its presence in the molecular structure can influence the pharmacokinetic and pharmacodynamic properties of the final drug product.
Used in Agrochemical Production:
In the agrochemical industry, Ethanone, 1-[4-(dimethylamino)-3-pyridinyl]-2,2,2-trifluoro(9CI) serves as an intermediate in the production of pesticides and other agrochemicals, where its unique structure can enhance the activity and selectivity of these compounds towards target pests.
Used in Medicinal Chemistry Research:
Ethanone, 1-[4-(dimethylamino)-3-pyridinyl]-2,2,2-trifluoro(9CI) is utilized in medicinal chemistry research as a building block for the design and synthesis of novel bioactive molecules. Its structural features allow for the exploration of new chemical space and the potential discovery of compounds with therapeutic applications.
Used in Organic Synthesis:
As a versatile reagent in organic synthesis, Ethanone, 1-[4-(dimethylamino)-3-pyridinyl]-2,2,2-trifluoro(9CI) is employed in various chemical reactions to construct complex organic molecules. Its fluorinated ketone and pyridine ring functionalities offer unique opportunities for the formation of diverse chemical products.

Check Digit Verification of cas no

The CAS Registry Mumber 230305-72-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,3,0,3,0 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 230305-72:
(8*2)+(7*3)+(6*0)+(5*3)+(4*0)+(3*5)+(2*7)+(1*2)=83
83 % 10 = 3
So 230305-72-3 is a valid CAS Registry Number.

230305-72-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-trifluoroacetyl-4-dimethylaminopyridine

1.2 Other means of identification

Product number -
Other names 1-(4-(Dimethylamino)pyridin-3-yl)-2,2,2-trifluoroethanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:230305-72-3 SDS

230305-72-3Relevant articles and documents

Site-selective trifluoroacetylation of dimethylamino-substituted pyridines and its use as a building block for trifluoromethyl-containing heterocycles

Kawase, Masami,Koyanagi, Jyunichi,Saito, Setsuo

, p. 718 - 719 (1999)

Trifluoroacetyl pyridine derivatives are conveniently prepared, and applied to the synthesis of trifluoromethyl-substituted pyrazolo[4,3- c]pyridine derivatives.

PYRAZOLEALKANAMIDE SUBSTITUTED THIOPHENES AS AMPA POTENTIATORS

-

Page/Page column 83-84, (2008/06/13)

The present invention relates to a heterocyclic derivative according to Formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceuti

A simple synthetic method for 3-trifluoroacetylated 4-aminoquinolines from 4-dimethylaminoquinoline by novel trifluoroacetylation and N-N exchange reactions

Okada, Etsuji,Sakaemura, Takushi,Shimomura, Naofumi

, p. 50 - 51 (2007/10/03)

Acylation of 4-dimethylaminoquinoline with 1-trifluoroacetyl-4-dimethylaminopyidinium trifluoroacetate proceeded cleanly to give 3-trifluoroacetyl-4-dimethylaminoquinoline, which underwent nucleophilic aromatic substitutions with various amines to afford

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