2351-42-0Relevant articles and documents
Tumor nano vaccine Preparation method and application thereof
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Paragraph 0057-0059, (2021/11/03)
The invention relates to a tumor nano vaccine and a preparation method and application thereof. The tumor nano vaccine is a composite nano micelle composed of an acid sensitive polymer immunologic adjuvant conjugate and a tumor-related antigen/antigen peptide, and the acid sensitive polymer immunoadjuvant conjugate has the structure shown 1. The tumor nano vaccine can selectively target lymph nodes and efficiently deliver tumor neoantigen and immunologic adjuvant to dendritic cells, activate antigen-specific T-cell immune effect, and efficiently inhibit tumor growth and metastasis.
Phosphate cross-linking agent and preparation method thereof, phosphate-based cross-linked gel polymer electrolyte and preparation method and application thereof
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Paragraph 0047-0048; 0055, (2020/08/17)
According to the invention, the safety of the battery can be improved based on introduction of phosphate into the gel polymer electrolyte, , the adjustable flexibility is improved by introduction of aPEO chain segment, and the stability and the polymerization capability are improved by introduction of acrylate; thus, further research is carried out on the basis of the prior art, the polyfunctional phosphate cross-linking agent is obtained and is applied to the preparation of the phosphate-based cross-linked gel polymer electrolyte, so the cross linking agent can be copolymerized with other functional monomers to synthesize gel polymer electrolyte; the gel polymer electrolyte has the advantages of simple and convenient preparation method, high ionic conductivity, high thermal stability andgood electrochemical stability, the assembled sodium ion battery has good cycling stability and high-temperature performance, and the phosphate-based gel polymer electrolyte with high safety is provided for quasi-solid sodium/lithium ion batteries.
Protein-Grafted Polymers Prepared Through a Site-Specific Conjugation by Microbial Transglutaminase for an Immunosorbent Assay
Wakabayashi, Rie,Yahiro, Kensuke,Hayashi, Kounosuke,Goto, Masahiro,Kamiya, Noriho
, p. 422 - 430 (2017/02/23)
Protein-polymer conjugates have been developed in many fields. Most hybrids are composed of one protein attached to one or several polymer chains. The other form of hybrid involves the construction of multiple proteins on one polymer chain, thereby facili