23564-81-0

Basic information

• Product Name: o-Chloro-N-phenylbenzamidine
• Synonyms: o-Chloro-N-phenylbenzamidine
• CAS NO: 23564-81-0
• Molecular Formula: C₁₃H₁₁ClN₂
• Molecular Weight: 230.69
• Mol File: 23564-81-0.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: o-Chloro-N-phenylbenzamidine(CAS DataBase Reference)
• NIST Chemistry Reference: o-Chloro-N-phenylbenzamidine(23564-81-0)
• EPA Substance Registry System: o-Chloro-N-phenylbenzamidine(23564-81-0)

Safety Data

• Hazardous Substances Data: 23564-81-0(Hazardous Substances Data)

Upstream product

• 873-32-5 2-Chlorobenzonitrile 
• 62-53-3 aniline 
• 4484-20-2 aniline benzenesulfonate 

Downstream Products

• 99806-12-9 (3aR,9aS)-2-(2-Chloro-phenyl)-4-methyl-1-phenyl-3a,4,9,9a-tetrahydro-1H-imidazo[4,5-b]quinoxaline; hydriodide 
• 132141-38-9 2,N-Dichloro-N'-phenylbenzamidine 
• 1423125-95-4 2-(2-chlorophenyl)-1,4-diphenyl-1H-imidazole 
• 7716-65-6 N-phenylbenzo[d]isothiazol-3-amine 
• 14959-62-7 2-phenyl-3-phenylisoquinolin-1-one 
• 14959-66-1 3-(4-methylphenyl)-2-phenyl-1(2H)-isoquinolone 
• 1448450-25-6 3-(4-fluorophenyl)-2-phenylisoquinolin-1(2H)-one 
• 1448450-26-7 3-(4-bromophenyl)-2-phenylisoquinolin-1(2H)-one 
• 1040255-59-1 3,4-dibutyl-2-phenylisoquinolin-1(2H)-one 
• 14959-72-9 2,3,4-triphenylisoquinolin-1(2H)-one 
• 1073486-93-7 2,3-diphenyl-4-carboxylic acid ethyl ester-isoquinolin-1(2H)-one 
• 758640-21-0 N-Benzylaniline 

Relevant articles and documents

A single step synthesis of 6-aminophenanthridines from anilines and 2-chlorobenzonitriles

Biologically active 6-aminophenanthridines were prepared in a single step procedure: Metal amides in liquid ammonia promoted the condensation of anilines with 2-chloro-benzonitriles. 6-Aminophenanthridines were isolated in moderate yield.

An eco-friendly approach for the synthesis of 1,2,5-trisubstituted and 4-amino-1,2,5-tetrasubstituted imidazoles via a multi-component condensation

The synthesis of 1,2,5-trisubstituted and 4-amino-1,2,5-tetrasubstituted imidazoles was demonstrated via a two-step cyclo-condensation reaction of aryl amines, carbonitriles, and ethyl bromopyruvate or aryl amines and arylglyoxals in ethanol heated under

Base-Mediated Amination of Alcohols Using Amidines

Novel and efficient base-mediated N-alkylation and amidation of amidines with alcohols have been developed, which can be carried out in one-pot reaction conditions, which allows for the synthesis of a wide range of N-alkyl amines and free amides in good to excellent yields with high atom economy. In contrast to borrowing hydrogen/hydrogen autotransfer or oxidative-type N-alkylation reactions, in which alcohols are activated by transition-metal-catalyzed or oxidative aerobic dehydrogenation, the use of amidines provides an effective surrogate of amines. This circumvents the inherent necessity in N-alkylation of an oxidant or a catalyst to be stabilized by ligands.