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235744-89-5

5'-O-(tert-butyldimethylsilyl)-(N3-benzoyl)thymidine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 3-benzoyl-1-((2R,4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

    Cas No: 235744-89-5

  • USD $ 1.9-2.9 / Gram

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  • 235744-89-5 Structure

  • Basic information

    1. Product Name: 5'-O-(tert-butyldimethylsilyl)-(N3-benzoyl)thymidine
    2. Synonyms: 5'-O-(tert-butyldimethylsilyl)-(N3-benzoyl)thymidine
    3. CAS NO:235744-89-5
    4. Molecular Formula:
    5. Molecular Weight: 460.602
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 235744-89-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5'-O-(tert-butyldimethylsilyl)-(N3-benzoyl)thymidine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5'-O-(tert-butyldimethylsilyl)-(N3-benzoyl)thymidine(235744-89-5)
    11. EPA Substance Registry System: 5'-O-(tert-butyldimethylsilyl)-(N3-benzoyl)thymidine(235744-89-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 235744-89-5(Hazardous Substances Data)

235744-89-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 235744-89-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,3,5,7,4 and 4 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 235744-89:
(8*2)+(7*3)+(6*5)+(5*7)+(4*4)+(3*4)+(2*8)+(1*9)=155
155 % 10 = 5
So 235744-89-5 is a valid CAS Registry Number.

235744-89-5Relevant articles and documents

Photo-cleavable nucleotides for primer free enzyme mediated DNA synthesis

Mathews, Anu Stella,Yang, Haikang,Montemagno, Carlo

, p. 8278 - 8288 (2016)

The synthesis, characterization and potential application of eight 3′-O modified 2′-deoxyribonucleoside triphosphates (dNTPs) are discussed. These nucleotide analogues are modified by capping the 3′-OH with a photolabile protecting group which can temporarily cease DNA strand growth and can smoothly reinitiate the growth by the photodecomposition of the protecting group and setting the 3′-OH of dNTPs free to propagate. The synthesis of 3′-O-(2-nitrobenzyl)-2′-deoxyribonucleoside triphosphates (NB-dNTPs) and 3′-O-(4,5-dimethoxy-2-nitrobenzyl)-2′-deoxyribonucleoside triphosphates (DMNB-dNTPs) is discussed in detail with structural confirmation using NMR. The UV-cleaving studies are monitored and quantified using LCMS and 1H NMR spectral traces. The synthesised nucleotides are employed for terminating and reinitiating template-less DNA synthesis, using primer independent Terminal Deoxynucleotidyl Transferase (TdT) enzyme. The use of this photolabile nucleotide in one step stop-start DNA synthesis is a novel strategy towards the precise assembly of dNTPs with the potential to reinforce present technologies.

A simple and convenient method for the deprotection of tetrahydropyranyl ether using iodine in methanol

Ramasamy, Kanda S.,Bandaru, Rajanikanth,Averett, Devron

, p. 2881 - 2894 (2007/10/03)

A simple and efficient method for the deprotection of tetrahydropyranyl and 4,4'-dimethoxytrityl ethers using iodine in methanol is described.

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