2388-69-4Relevant articles and documents
t-BuOK-promoted methylthiolation of aryl fluorides with dimethyldisulfide under transition-metal-free and mild conditions
Huang, Dayun,Wu, Xiangmei
, (2021/03/24)
In the presence of potassium tert-butoxide (t-BuOK), the cross-coupling reaction between aryl fluorides and dimethyldisulfide was developed. A series of aryl methyl sulfides were obtained in moderate to good yields under transition-metal-free and mild conditions.
Copper-Catalyzed Methylthiolation of Aryl Iodides and Bromides with Dimethyl Disulfide in Water
Wang, Ying-Yu,Wu, Xiang-Mei,Yang, Ming-Hua
supporting information, (2020/07/20)
An efficient route to aryl methyl sulfides through the copper-catalyzed coupling reaction of aryl iodides or bromides with dimethyl disulfide in water is described. Electron-donating and electron-withdrawing functional groups in the substrates were tolerated, and the corresponding products were obtained in moderate to good yields.
A novel donor-π-acceptor halochromic 2,6-distyrylnaphthalene chromophore: synthesis, photophysical properties and DFT studies
Panahi, Farhad,Mahmoodi, Ali,Ghodrati, Sajjad,Eshghi, Fazlolah
, p. 168 - 176 (2021/02/09)
In this study a new 2,6-distyryl naphthalene [2-((4-((E)-2-(6-((E)-2,4-bis(methylsulfonyl)styryl)naphthalen-2-yl)vinyl)phenyl)(ethyl)amino)ethan-1-ol;ASDSN] was synthesized successfully using Heck chemistry as the main reaction. TheASDSNcompound is a dono
Glucagon antagonists/inverse agonists
-
, (2008/06/13)
Disclosed is a novel class of compounds of formula (I) wherein V, A, Y, Z, R1, E, X and D are as defined in the specification. These compounds act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to their antagonizing effect of the glucagon receptor, the compounds are suitable for treating or preventing glucagon-mediated conditions and diseases such as hyperglycemia, Type 1 diabetes, Type 2 diabetes and obesity.
1,3-Dilithiobenzene and 1,4-Dilithiobenzene
Fossatelli, M.,Besten, R. den,Verkruijsse, H. D.,Brandsma, L.
, p. 527 - 528 (2007/10/02)
Using the method of iodine-lithium exchange, 1,3- and 1,4-dilithiobenzene have been generated in solution and isolated in a dry state for the first time.The dilithium compounds are not formed from the corresponding dibromobenzenes.
Enantioselective Oxidation of Thioethers: an Easy Route to Enantiopure C2 Symmetrical bis-Methylsulfinylbenzenes
Bendazzoli, Paolo,Furia, Fulvio Di,Licini, Giulia,Modena, Giorgio
, p. 2975 - 2978 (2007/10/02)
The direct oxidation of bis-methylthioethers 1 by t-butyl hydroperoxide, titanium tetra-isopropylate and (+)-diethyl tartrate, affords the almost enantiomerically pure dl bis-methylsulfinylbenzenes 2 (e.e. >/= 99percent) in a process which is also charact
DIMETALLATION OF BENZENE
Lochmann, L.,Fossatelli, M.,Brandsma, L.
, p. 529 - 530 (2007/10/02)
Using the combination of n-butyllithium and soluble potassium t-alkoxides higher ratios of di- and mono-metallated benzene have been attained with n-butyllithium and the insoluble t-BuOK.
SYNTHESIS AND CYCLOPROPANATION OF E,E AND Z,Z-1,3-BIS(STYRYLSULFONYL)BENZENE
Reddy, M. V. Ramana,Reddy, S.,Reddy, P. V. Ramana,Reddy, D. Bhaskar,Reddy, N. Subba
, p. 123 - 128 (2007/10/02)
The synthesis of 1,3-bis(styrylsulfonyl)benzene in two isomeric forms (Z,Z and E,E) and their cyclopropanation with dimethylsulfonium methylide has been described.The configurational assigments of these compounds have been made on the basis of IR,1H NMR a
Fragmentation of Aryl Alkyl Sulfides. A Simple, One-Pot Synthesis of Polymercaptobenzenes from Polychlorobenzenes
Maiolo, Filippo,Testaferri, Lorenzo,Tiecco, Marcello,Tingoli, Marco
, p. 3070 - 3073 (2007/10/02)
A simple procedure is described which allows one to prepare polymercaptobenzenes starting from chlorobenzenes.The reactions of all the possible chlorobenzenes with Me2CHSNa in HMPA give the corresponding (isopropylthio)benzenes which can be cleaved by adding sodium to the reaction mixtures to give the arenethiolates in good yields.In some cases the polymercaptobenzenes were isolated after treatment with acid; in other cases methyl iodide was added to the reaction mixture and poly(methylthio)benzenes were obtained.It is suggested that the (isopropylthio)benzenes react with sodium to give the corresponding radical anions which fragment at the sulfur-alkyl bond to give the arenethiolates.