2388-69-4

Basic information

• Product Name: 1,3-bis(methylsulfanyl)benzene
• Synonyms: 1,3-Bis(methylsulfanyl)benzene; benzene, 1,3-bis(methylthio)-
• CAS NO: 2388-69-4
• Molecular Formula: C₈H₁₀S₂
• Molecular Weight: 170.295
• Mol File: 2388-69-4.mol

Chemical Properties

• Boiling Point: 257.1°C at 760 mmHg
• Flash Point: 110.1°C
• Density: 1.13g/cm³
• Vapor Pressure: 0.0238mmHg at 25°C
• Refractive Index: 1.607
• CAS DataBase Reference: 1,3-bis(methylsulfanyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis(methylsulfanyl)benzene(2388-69-4)
• EPA Substance Registry System: 1,3-bis(methylsulfanyl)benzene(2388-69-4)

Safety Data

• Hazardous Substances Data: 2388-69-4(Hazardous Substances Data)

Upstream product

• 626-04-0 3-mercaptothiophenol 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 624-92-0 Dimethyldisulphide 
• 71-43-2 benzene 
• 626-00-6 1,3-Diiodobenzene 
• 372-18-9 1,3-Difluorobenzene 
• 121-47-1 3-aminobenzenesulfonic acid 
• 87-61-6 1,2,3-trichlorobenzene 
• 541-73-1 1,3-Dichlorobenzene 
• 74-93-1 methylthiol 
• 109-79-5 n-butanethiol 
• 36051-39-5 sodium phenylene-1,2-dithiolate 

Downstream Products

• 3996-33-6 <3-(methylthio)phenylthio>acetic acid 
• 22821-85-8 1,3-bis(methanesulfonyl)benzene 
• 150513-89-6 1,3-bis-methanesulfinyl-benzene 
• 78227-85-7 2,4-bis(methylthio)nitrobenzene 
• 78176-67-7 1,3-dithiomethoxy-4,6-dichlorobenzene 
• 861601-41-4 1,3-bis-trichloromethylsulfanyl-benzene 
• 1026274-06-5 2,4-bis(methylthio)bromobenzene 
• 100-68-5 methyl-phenyl-thioether 
• 65052-48-4 3-cyanophenyl methyl sulfide 
• 78637-29-3 [W(CO)5]2(μ-C6H4-m-(SCH3)2) 
• 78637-28-2 [Cr(CO)5]2(μ-C6H4-m-(SCH3)2) 
• 92958-74-2 4,6-Dimethylsulfon-1,3-diacetyl-benzol 
• 91844-40-5 4,6-Dimethylmercapto-1,3-bis-bromacetyl-benzol 
• 92904-36-4 4,6-Dimethylmercapto-1,3-bis-<1-hydroxy-aethyl>-benzol 

Relevant articles and documents

t-BuOK-promoted methylthiolation of aryl fluorides with dimethyldisulfide under transition-metal-free and mild conditions

In the presence of potassium tert-butoxide (t-BuOK), the cross-coupling reaction between aryl fluorides and dimethyldisulfide was developed. A series of aryl methyl sulfides were obtained in moderate to good yields under transition-metal-free and mild conditions.

Copper-Catalyzed Methylthiolation of Aryl Iodides and Bromides with Dimethyl Disulfide in Water

An efficient route to aryl methyl sulfides through the copper-catalyzed coupling reaction of aryl iodides or bromides with dimethyl disulfide in water is described. Electron-donating and electron-withdrawing functional groups in the substrates were tolerated, and the corresponding products were obtained in moderate to good yields.

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Enantioselective Oxidation of Thioethers: an Easy Route to Enantiopure C2 Symmetrical bis-Methylsulfinylbenzenes

The direct oxidation of bis-methylthioethers 1 by t-butyl hydroperoxide, titanium tetra-isopropylate and (+)-diethyl tartrate, affords the almost enantiomerically pure dl bis-methylsulfinylbenzenes 2 (e.e. >/= 99percent) in a process which is also charact

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The synthesis of 1,3-bis(styrylsulfonyl)benzene in two isomeric forms (Z,Z and E,E) and their cyclopropanation with dimethylsulfonium methylide has been described.The configurational assigments of these compounds have been made on the basis of IR,1H NMR a

Fragmentation of Aryl Alkyl Sulfides. A Simple, One-Pot Synthesis of Polymercaptobenzenes from Polychlorobenzenes

A simple procedure is described which allows one to prepare polymercaptobenzenes starting from chlorobenzenes.The reactions of all the possible chlorobenzenes with Me2CHSNa in HMPA give the corresponding (isopropylthio)benzenes which can be cleaved by adding sodium to the reaction mixtures to give the arenethiolates in good yields.In some cases the polymercaptobenzenes were isolated after treatment with acid; in other cases methyl iodide was added to the reaction mixture and poly(methylthio)benzenes were obtained.It is suggested that the (isopropylthio)benzenes react with sodium to give the corresponding radical anions which fragment at the sulfur-alkyl bond to give the arenethiolates.