244246-71-7 Usage
Description
3-Bromo-2-trifluoromethylaniline is an organic compound characterized by the chemical formula C7H5BrF3N. It is a bromo-trifluoromethyl substituted aniline derivative, recognized for its significance in organic synthesis and the pharmaceutical industry. 3-Bromo-2-trifluoromethylaniline's distinctive structure and properties render it a valuable building block for the creation of new materials and compounds.
Uses
Used in Organic Synthesis:
3-Bromo-2-trifluoromethylaniline is utilized as a key intermediate in organic synthesis, contributing to the development of a variety of pharmaceuticals, agrochemicals, and other organic compounds. Its unique structure allows it to serve as a versatile component in the creation of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Bromo-2-trifluoromethylaniline is employed as a crucial intermediate for the synthesis of diverse pharmaceuticals. Its specific functional groups facilitate targeted drug design and the production of medications with specific therapeutic properties.
Used in Agrochemical Production:
3-Bromo-2-trifluoromethylaniline also finds application in the agrochemical sector, where it is used as an intermediate in the synthesis of various agrochemicals. Its role in this industry is pivotal for the development of effective crop protection agents and other agricultural products.
Used in Dyes and Pigments Production:
Furthermore, 3-Bromo-2-trifluoromethylaniline is used in the production of dyes and pigments, capitalizing on its chemical properties to create a range of colorants for various applications.
Safety Note:
It is important to handle 3-Bromo-2-trifluoromethylaniline with caution due to its potentially hazardous nature. Adequate safety measures should be implemented during its use to ensure the well-being of individuals and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 244246-71-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,4,2,4 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 244246-71:
(8*2)+(7*4)+(6*4)+(5*2)+(4*4)+(3*6)+(2*7)+(1*1)=127
127 % 10 = 7
So 244246-71-7 is a valid CAS Registry Number.
244246-71-7Relevant articles and documents
Nickel-Catalyzed Direct C-H Trifluoromethylation of Free Anilines with Togni's Reagent
Gao, Xianying,Geng, Yang,Han, Shuaijun,Liang, Apeng,Li, Jingya,Zou, Dapeng,Wu, Yusheng,Wu, Yangjie
supporting information, p. 3732 - 3735 (2018/07/22)
An efficient nickel-catalyzed C-H trifluoromethylation for the synthesis of trifluoromethylated free anilines using Togni's reagent has been developed. This approach exhibits a good functional group tolerance, good regioselectivity, and chemoselectivity under mild conditions. The newly developed economical one-step method is a better alternative to synthesize trifluoromethylated free anilines.
A for the preparation of ortho-trifluoromethyl-aniline or its derivatives (by machine translation)
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Paragraph 0041-0042, (2016/10/24)
The invention discloses a method for preparing o-trifluoromethyl phenylamine and derivatives thereof. According to the method, phenylamine or a phenylamine derivative serving as raw material reacts with a trivalent iodine reagent compound 2 in a solution under the protection of argon or nitrogen and illumination condition in the presence of tri(2-phenylpyridine)-iridium [Ir(ppy)3] serving as a catalyst to produce o-trifluorophenylamine or derivatives thereof 3, wherein the trivalent iodine reagent compound 2 has a structure shown in the specification. The method is mild in reaction conditions, the amino does not need to be protected, and trifluoromethyl substituted phenylamine or phenylamine derivatives can be directly obtained.
