2480-26-4

Basic information

• Product Name: H-L-MESER-OH HCL
• Synonyms: H-MESER-OH;H-L-MESER-OH HCL;N-METHYL-L-SERINE HYDROCHLORIDE;N-ME-SER-OH;N-ME-SER-OH HCL;N-ME-SERINE;N-ALPHA-METHYL-L-SERINE;N-ALPHA-METHYL-L-SERINE HYDROCHLORIDE
• CAS NO: 2480-26-4
• Molecular Formula: C4H10ClNO3
• Molecular Weight: 155.58
• EINECS: 200-258-5
• Product Categories: amino acid;amino acids
• Mol File: 2480-26-4.mol

Chemical Properties

• Melting Point: 190℃ (dec.)
• Boiling Point: 326.2 °C at 760 mmHg
• Flash Point: 151.1 °C
• Appearance: /
• Density: 1.242 g/cm³
• Vapor Pressure: 1.68E-05mmHg at 25°C
• Refractive Index: 1.479
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 2.17±0.10(Predicted)
• BRN: 2498641
• CAS DataBase Reference: H-L-MESER-OH HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-L-MESER-OH HCL(2480-26-4)
• EPA Substance Registry System: H-L-MESER-OH HCL(2480-26-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 2480-26-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
H-L-MESER-OH HCL is used as an active pharmaceutical ingredient for the development of drugs targeting various medical conditions. Its specific application reason in this industry is due to its unique chemical structure and potential therapeutic effects.
Used in Cosmetic Industry:
H-L-MESER-OH HCL is used as a topical compound in anti-aging agents, cosmetic peptides, and skin-conditioning agents. The application reason is its ability to improve skin health and appearance by promoting collagen production and providing moisturizing and anti-aging benefits.

InChI:InChI=1/C4H9NO3/c1-5-3(2-6)4(7)8/h3,5-6H,2H2,1H3,(H,7,8)/t3-/m0/s1

Upstream product

• 56-45-1 L-serin 
• 173947-21-2 N-benzyloxycarbonyl-N-methyl-L-serine 
• 50-00-0 formaldehyd 
• 106910-76-3 (S)-2-(benzylamino)-3-hydroxypropanoic acid 

Downstream Products

• 291311-48-3 Fmoc-N-methyl-L-serine 

Relevant articles and documents

General method for the synthesis of N-methyl amino acids and N-alkyl amino esters from O'Donnell's Schiff bases

N-methyl amino acids, including L-abrine, and N-alkyl amino esters, were synthesized by reductive amination of O'Donnell's Schiff base amino esters with NaBH3CN and formaldehyde, or the appropriate aldehyde in CH3CN or THF in good to excellent yields, and with high purity.

Selenoimidazolium Salts as Supramolecular Reagents for Protein Alkylation

Se-benzyl selenoimidazolium salts are characterized by remarkable alkyl-transfer potential under physiological conditions. Structure-activity relationship studies show that selective monoalkylation of primary amines depends on supramolecular interactions

Domino 1,3-dipolar cycloadditions of n- alkyl-α-amino esters with paraformaldehyde: A direct access to α-hydroxymethyl α-amino acids

N-Alkyl-α-amino esters undergo a domino reaction, based on the iminium cation generation, with paraformaldehyde, followed by a 1,3-dipolar cycloaddition of the stabilized azomethA?ine ylide with another equivalent of formaldehyde. The resulting products are oxazolidines, which can be transformed after hydrolysis into α-hydroxymethyl α-amino acid or its derivatives. The diastereoselective 1,3-dipolar cycloaddition was performed using sarcosine (-)-menthyl or (-)-8-phenylmenthyl esters affording the cyclic product with moderate enantiomeric ratio. Georg Thieme Verlag Stuttgart · New York.

The facile production of N-methyl amino acids via oxazolidinones

A range of oxazolidinones derived from N-carbamoyl α-amino acids were prepared by an efficient method as key intermediates in the synthesis of N-methyl amino acids and peptides. The method was readily applied to most α-amino acids except those with basic side chains. The oxazolidinones were converted by reductive cleavage into N-methyl α-amino acids. CSIRO 2000.