256379-30-3

Basic information

• Product Name: 2-Pyridinamine,3-methyl-N-2-propenyl-(9CI)
• Synonyms: 2-Pyridinamine,3-methyl-N-2-propenyl-(9CI)
• CAS NO: 256379-30-3
• Molecular Formula: C₉H₁₂N₂
• Molecular Weight: 148.20498
• Product Categories: PYRIDINE
• Mol File: 256379-30-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Pyridinamine,3-methyl-N-2-propenyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinamine,3-methyl-N-2-propenyl-(9CI)(256379-30-3)
• EPA Substance Registry System: 2-Pyridinamine,3-methyl-N-2-propenyl-(9CI)(256379-30-3)

Safety Data

• Hazardous Substances Data: 256379-30-3(Hazardous Substances Data)

Upstream product

• 1603-40-3 3-methylpyridin-2-ylamine 
• 106-95-6 allyl bromide 
• 107-05-1 3-chloroprop-1-ene 

Downstream Products

• 1007-32-5 benzyl ethyl ketone 

Relevant articles and documents

I2O5-Mediated Iodocyclization Cascade of N-(1-Arylallyl)pyridine-2-amines with Concomitant C=C Bond Cleavage: A Synthesis of 3-Iodoimidazo[1,2- a]pyridines

A facile method for the synthesis of 3-iodoimidazo[1,2-a]pyridines has been successfully developed involving an I2O5-mediated iodocyclization cascade of N-(1-arylallyl)pyridin-2-amines with concomitant C=C bond cleavage. Preliminary mechanistic studies reveal that this protocol might undergo an oxidative cyclization/decarboxylation/iodination sequence in which I2O5 is used as both an oxidant and an iodine source. The present protocol has advantages of wide substrate scope, simple operation, and metal-free conditions.

Copper-catalyzed intramolecular dehydrogenative aminooxygenation: Direct access to formyl-substituted aromatic N-heterocycles

A direct synthesis of carbaldehydes through intramolecular dehydrogenative aminooxygenation has been developed. The process uses a catalytic amount of copper(II) in DMF or DMA under oxygen and does not require additional oxidants (see scheme). Mechanistic studies suggest that the carbonyl oxygen atom of the aldehyde is derived from oxygen through a copper-mediated oxygen activation process via a peroxy-copper(III) intermediate. Copyright

Catalytic activation of C-H and C-C bonds of allylamines via olefin isomerization by transition metal complexes

(matrix presented) The metal-catalyzed reaction of olefins with allylamines bearing coordination sites (2-pyridyl groups) was studied. With Ru3(CO)12 as catalyst, activation of C-H bonds led to the formation of ketimines that were hydrolyzed to give asymmetric ketones. With [(C8H14)2RhCl]2, both C-H and C-C bonds were activated and symmetric ketones were formed on hydrolysis. The reaction involves double bond migration of the allylamine to form an aldimine.