27532-96-3

Basic information

• Product Name: Glycine tert butyl ester hydrochloride
• Synonyms: GLYCIN-TERT-BUTYL ESTER HYDROCHLORIDE;GLYCINE T-BUTYL ESTER HCL;GLYCINE T-BUTYL ESTER HYDROCHLORIDE;GLYCINE T-BUTYL ESTER HYDROCHLORIDE SALT;GLYCINE TERT-BUTYL ESTER HYDROCHLORIDE;GLYCINE-OTBU HCL;H-GLY-OTBU HCL;H-GLY-OTBU HYDROCHLORIDE
• CAS NO: 27532-96-3
• Molecular Formula: C₆H₁₄NO₂*Cl
• Molecular Weight: 167.63
• EINECS: 214-223-8
• Product Categories: Miscellaneous;Amino Acids;Glycine [Gly, G];Amino Acids and Derivatives;Amino Acids 13C, 2H, 15N;Amino Acid tert-Butyl Esters;Amino Acids (C-Protected);Biochemistry;Amino hydrochloride;Amino Acids & Derivatives
• Mol File: 27532-96-3.mol

Chemical Properties

• Melting Point: 141-143 °C(lit.)
• Boiling Point: 145.7 °C at 760 mmHg
• Flash Point: 20.7 °C
• Appearance: White/Crystalline Powder
• Density: 0.973 g/cm³
• Vapor Pressure: 0.026mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: −20°C
• Solubility: H2O: 0.1 g/mL, clear, colorless
• Water Solubility: Soluble in methanol and water
• BRN: 3989048
• CAS DataBase Reference: Glycine tert butyl ester hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine tert butyl ester hydrochloride(27532-96-3)
• EPA Substance Registry System: Glycine tert butyl ester hydrochloride(27532-96-3)

Safety Data

• Statements: 36/37/38
• Safety Statements: 24/25
• WGK Germany: 3
• F: 10-23
• TSCA: No
• Hazardous Substances Data: 27532-96-3(Hazardous Substances Data)

Usage

Uses

1. Used in Pharmaceutical Industry:
Glycine tert butyl ester hydrochloride is used as a parakeratosis inhibitor for the treatment of skin conditions. Its application reason is based on its ability to inhibit the abnormal keratinization process, which is a common feature in various skin disorders.
2. Used in Cosmetics and Skincare Industry:
Glycine tert butyl ester hydrochloride is used as an external composition for skin care products. The application reason is its potential to improve skin health by addressing parakeratosis, a condition that leads to dry, flaky skin, and can be associated with various skin issues such as eczema and psoriasis.

InChI:InChI=1/C9H9NO/c1-7-3-4-8(6-10)5-9(7)11-2/h3-5H,1-2H3

Downstream Products

• 50903-74-7 carbobenzoxy-L-asparaginylglycine tert-butyl ester 
• 19811-56-4 hippuric acid tert-butyl ester 
• 81477-94-3 N-(diphenylmethylene)glycine tert-butyl ester 
• 114703-82-1 N-cyclohexyl-N-methyl-4-<<2-amino-3-<(tert-butyloxycarbonyl)methyl>-3,4-dihydroquinazolin-6-yl>oxy>butyramide hydrobromide 
• 111652-20-1 N-(tert-butoxycarbonyl)glycine tert-butyl ester 
• 117833-60-0 N-tert-butoxycarbonyl-α-bromoglycine tert-butyl ester 
• 132866-45-6 N-Benzyloxycarbonyl-L-seryl(O-tert-butyl)-glycine tert-butyl ester 
• 74085-05-5 tert-butylbenzyloxycarbonyl-(D)alanylglicinate 
• 95605-15-5 {[1-p-Tolyl-meth-(E)-ylidene]-amino}-acetic acid tert-butyl ester 
• 105001-57-8 Z-Lys(BOC)-Gly-O-t-Bu 
• 101055-28-1 tert-butyl diphenylphosphorylglycinate 
• 88463-15-4 TFA-Gly-ΔAla-Gly-OtBu 
• 101055-31-6 {3-Azido-2-[2-(2,2,2-trifluoro-acetylamino)-acetylamino]-propionylamino}-acetic acid tert-butyl ester 
• 101055-22-5 TFA-Val-ΔAla-Gly-OtBu 

Relevant articles and documents

Carboxy, carboalkoxy and carbamile substituted isonitrile radionuclide complexes

A coordination complex comprising a radionuclide selected from the class consisting of radioactive isotopes of Tc, Ru, Co, Pt and Re and an isonitrile ligand of the formula: where X is a lower alkyl group having 1 to 4 carbon atoms, wherein R is selected from the group consisting of COOR1 and CONR2 R3 where R1 can be H, a pharmaceutically acceptable cation, or a substituted or unsubstituted alkyl group having 1 to 4 carbon atoms, R2, and R3 can be H, or a substituted or unsubstituted alkyl group having 1 to 4 carbon atoms, and R2 and R3 can be the same or different is disclosed. Kits that can be used to form these complexes are also disclosed.