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4-(Isopropylamino)-3-nitrobenzoic acid is a chemical compound that features a benzene ring with a nitro group and an isopropylamino group attached to it. 4-(ISOPROPYLAMINO)-3-NITROBENZOIC ACID is recognized for its potential applications in drug development and research within the fields of biology and chemistry.

284672-95-3

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284672-95-3 Usage

Uses

Used in Pharmaceutical Research and Development:
4-(Isopropylamino)-3-nitrobenzoic acid is used as a building block for the synthesis of various compounds, particularly in the creation of pharmaceutical drugs. Its unique structure allows it to be a versatile component in the development of new medications.
Used as a pH-Sensitive Probe in Biological Systems:
Due to the presence of the isopropylamino group, 4-(Isopropylamino)-3-nitrobenzoic acid is utilized as a pH-sensitive probe for studying biological systems. This feature makes it valuable for monitoring and analyzing changes in pH levels within complex biological environments.
Used for its Electron-Withdrawing Properties in Synthetic Chemistry:
The nitro group in 4-(Isopropylamino)-3-nitrobenzoic acid provides electron-withdrawing properties that are beneficial in synthetic chemistry. This characteristic is harnessed to facilitate various chemical reactions and the synthesis of a range of chemical products.

Check Digit Verification of cas no

The CAS Registry Mumber 284672-95-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,4,6,7 and 2 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 284672-95:
(8*2)+(7*8)+(6*4)+(5*6)+(4*7)+(3*2)+(2*9)+(1*5)=183
183 % 10 = 3
So 284672-95-3 is a valid CAS Registry Number.

284672-95-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(Isopropylamino)-3-nitrobenzoic acid

1.2 Other means of identification

Product number -
Other names 3-nitro-4-(propan-2-ylamino)benzoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:284672-95-3 SDS

284672-95-3Relevant articles and documents

Oxygen-containing five-membered heterocyclic compound, synthesis method, pharmaceutical composition and application

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Paragraph 0125; 0145; 0150, (2020/11/10)

The invention discloses an oxygen-containing five-membered heterocyclic compound, a synthesis method, a pharmaceutical composition and application thereof, and belongs to the technical field of medicines and preparation and application thereof. The oxygen-containing five-membered heterocycle has the biological activity of inhibiting the protein tyrosine phosphatase SHP2, can be used as a tool compound for researching the biological function relevance of the protein tyrosine phosphatase SHP2 in the cell signal transduction process, and provides a new means for preventing and treating cancers and metabolic and immune diseases.

3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b

Skinner, Philip J.,Cherrier, Martin C.,Webb, Peter J.,Sage, Carleton R.,Dang, Huong T.,Pride, Cameron C.,Chen, Ruoping,Tamura, Susan Y.,Richman, Jeremy G.,Connolly, Daniel T.,Semple, Graeme

, p. 6619 - 6622 (2008/04/02)

A series of 3-nitro-4-substituted-aminobenzoic acids were prepared and found to act as potent and highly selective agonists of the orphan human GPCR GPR109b, a low affinity receptor for niacin. No activity was observed at the closely homologous high affinity niacin receptor, GPR109a. A second series, comprising 6-amino-substituted nicotinic acids was, also prepared and several analogues showed comparable activity to the nitroaryl series.

1-Alkyl-benzotriazole-5-carboxylic acids are highly selective agonists of the human orphan G-protein-coupled receptor GPR109b

Semple, Graeme,Skinner, Philip J.,Cherrier, Martin C.,Webb, Peter J.,Sage, Carleton R.,Tamura, Susan Y.,Chen, Ruoping,Richman, Jeremy G.,Connolly, Daniel T.

, p. 1227 - 1230 (2007/10/03)

1-Substituted benzotriazole carboxylic acids have been identified as the first reported examples of selective small-molecule agonists of the human orphan G-protein-coupled receptor GPR109b (HM74), a low-affinity receptor for the HDL-raising drug niacin. N

BENZOTRIAZOLES AND METHODS OF PROPHYLAXIS OR TREATMENT OF METABOLIC-RELATED DISORDERS THEREOF

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Page/Page column 47-48, (2008/06/13)

The present invention relates to certain benzotriazole carboxylic acid or ester derivatives of Formula (I), pharmaceutically acceptable salts and solvates thereof, which exhibit useful pharmaceutical properties, for example, as agonists for the GPCR refer

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