294188-25-3

Basic information

• Product Name: L-threo-Pentitol, 4-deoxy-1,3-bis-O-(phenylmethyl)-
• Synonyms: L-threo-Pentitol, 4-deoxy-1,3-bis-O-(phenylmethyl)-
• CAS NO: 294188-25-3
• Molecular Formula: C₁₉H₂₄O₄
• Molecular Weight: 316.39
• Mol File: 294188-25-3.mol

Chemical Properties

• Boiling Point: 494.5±45.0 °C(Predicted)
• Appearance: /
• Density: 1.154±0.06 g/cm3(Predicted)
• PKA: 13.53±0.20(Predicted)
• CAS DataBase Reference: L-threo-Pentitol, 4-deoxy-1,3-bis-O-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: L-threo-Pentitol, 4-deoxy-1,3-bis-O-(phenylmethyl)-(294188-25-3)
• EPA Substance Registry System: L-threo-Pentitol, 4-deoxy-1,3-bis-O-(phenylmethyl)-(294188-25-3)

Safety Data

• Hazardous Substances Data: 294188-25-3(Hazardous Substances Data)

Upstream product

• 294188-24-2 3,5-di-O-acetyl-2-deoxy-L-threo-pentono-1,4-lactone 
• 5336-08-3 D-Ribono-1,4-lactone 
• 78185-09-8 2-deoxy-D-ribonolactone-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one 
• 82130-86-7 2,5-di-O-tosyl-D-ribono-1,4-lactone 
• 91510-99-5 (2S,3R)-(3-hydroxy-5-oxotetrahydrofuran-2-yl)methyl 4-methylbenzenesulfonate 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 158976-98-8 3,5-di-O-benzyl-2-deoxy-L-threo-pentono-1,4-lactone 

Downstream Products

• 1054683-61-2 methanesulfonic acid (1S,2S)-2-benzyloxy-1-benzyloxymethyl-4-methanesulfonyloxybutyl ester 
• 294188-27-5 N-benzyl-3,5-di-O-benzyl-1,2,4-trideoxy-1,4-imino-D-erythro-pentitol 
• 294188-28-6 3,5-di-O-benzyl-1,2,4-trideoxy-1,4-imino-D-erythro-pentitol 
• 98900-30-2 (2R,3S)-2-hydroxymethyl-3-hydroxypyrrolidinium hydrochloride 

Relevant articles and documents

A new DNA building block, 4′-selenothymidine: Synthesis and modification to 4′-seleno-AZT as a potential anti-HIV agent

The first synthesis of 4′-selenothymidine (1), a novel DNA building block, and 4′-seleno-AZT (2) was accomplished from 2-deoxy-d-ribose via stereoselective formation of 2-deoxy-4-seleno-d-furanose 17 and a Pummerer-type base condensation as key steps. 4′-

A new stereospecific synthesis of 1,2,4-Trideoxy-1,4-imino-D-erythro-pentitol

1,2,4-Trideoxy-1,4-imino-D-erythro-pentitol [(2R,3S)-3-hydroxy-2-hydroxymethylpyrrolidine] (4) was synthesised from 2,5-di-O-tosyl-D-ribono-1,4-lactone in 42 % overall yield. The key steps were deoxygenation at C-2 and a stereospecific inversion of the co