1054683-61-2Relevant academic research and scientific papers
A new DNA building block, 4′-selenothymidine: Synthesis and modification to 4′-seleno-AZT as a potential anti-HIV agent
Alexander, Varughese,Choi, Won Jun,Chun, Jeongha,Kim, Hea Ok,Jeon, Ji Hye,Tosh, Dilip K.,Lee, Hyuk Woo,Chandra, Girish,Choi, Jungwon,Jeong, Lak Shin
supporting information; experimental part, p. 2242 - 2245 (2010/08/05)
The first synthesis of 4′-selenothymidine (1), a novel DNA building block, and 4′-seleno-AZT (2) was accomplished from 2-deoxy-d-ribose via stereoselective formation of 2-deoxy-4-seleno-d-furanose 17 and a Pummerer-type base condensation as key steps. 4′-
A new stereospecific synthesis of 1,2,4-Trideoxy-1,4-imino-D-erythro-pentitol
Malle, Birgitte Molholm,Lundt, Inge,Furneaux, Richard H.
, p. 573 - 583 (2007/10/03)
1,2,4-Trideoxy-1,4-imino-D-erythro-pentitol [(2R,3S)-3-hydroxy-2-hydroxymethylpyrrolidine] (4) was synthesised from 2,5-di-O-tosyl-D-ribono-1,4-lactone in 42 % overall yield. The key steps were deoxygenation at C-2 and a stereospecific inversion of the co
