30217-45-9Relevant articles and documents
Chemistry and structure of diterpene compounds of the kaurane series: IV. Acylation of reduction products of the isosteviol keto group
Al'fonsov,Bakaleinik,Gubaidullin,Kataev,Kovylyaeva,Konovalov,Litvinov,Strobykina,Andreeva,Korochkina
, p. 1144 - 1148 (2001)
Acetylation with acetic anhydride of (4α,8β,13β)-16-hydroxy-13-methyl-17-norkaurane-18-carboxylic acid and its methyl ester, obtained by reduction of isosteviol and (4α,8β,13β)-18-methoxycarbonyl-13-methyl-16-oxo-17-norkaurane, respectively, gives rise to
Design and synthesis of an α-mannosyl terpenoid as selective inhibitor of P-selectin
Ikeda, Tsuyoshi,Kajimoto, Tetsuya,Kondo, Hirosato,Wong, Chi-Huey
, p. 2485 - 2490 (2007/10/03)
In an effort to develop the structural and functional mimics of the tetrasaccharide sialyl Lewis x as selective inhibitors of P-selectin, we have designed a mannosyl terpenoid derivative that selectively inhibits P-selectin within an IC50 value of 60 μM, but exhibits no inhibition activity against E- and L-selectins.