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Cas Database

304480-84-0

304480-84-0

Identification

  • Product Name:methyl 4-(2-benzoylhydrazino)-4-oxobutanoate

  • CAS Number: 304480-84-0

  • EINECS:

  • Molecular Weight:250.254

  • Molecular Formula: C12H14N2O4

  • HS Code:

  • Mol File:304480-84-0.mol

Synonyms:methyl 4-(2-benzoylhydrazino)-4-oxobutanoate

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Relevant articles and documentsAll total 1 Articles be found

PURINONE DERIVATIVES AS HM74A AGONISTS

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Page/Page column 69-70, (2008/06/13)

The present invention relates to purinone derivatives which are agonists of the HM74a receptor. Further provided are compositions and methods of using the compounds herein, and their pharmaceutically acceptable salts for the treatment of disease.

Process route upstream and downstream products

Process route

methyl hydrogen succinate
3878-55-5

methyl hydrogen succinate

benzoic acid hydrazide
613-94-5

benzoic acid hydrazide

methyl 4-(2-benzoylhydrazino)-4-oxobutanoate
304480-84-0

methyl 4-(2-benzoylhydrazino)-4-oxobutanoate

Conditions
Conditions Yield
With dmap; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;
32.6%
methyl hydrogen succinate
3878-55-5

methyl hydrogen succinate

benzoic acid hydrazide
613-94-5

benzoic acid hydrazide

methyl 4-(2-benzoylhydrazino)-4-oxobutanoate
304480-84-0

methyl 4-(2-benzoylhydrazino)-4-oxobutanoate

Conditions
Conditions Yield
With dmap; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;
32.6%

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