3878-55-5Relevant articles and documents
Synthesis of alaremycin
Wang, Yong-Gang,Wachi, Masaaki,Kobayashi, Yuichi
, p. 481 - 483 (2006)
Methyl 5-azido-4-oxohexanoate was synthesized from 5-hexenoic acid in six steps and converted to the title compound by NaReO4- and CF 3SO3H-catalyzed reaction in Ac2CVCCl4 followed by hydrolysis of the methyl ester moiety. Georg Thieme Verlag Stuttgart.
Complex Formation of Calcium Ions and Monosubstituted Succinic Acid Derivatives in Aqueous Solutions
Mitrofanova
, p. 17 - 19 (2003)
Complex formation of calcium ions with succinic acid monoamide and methyl hydrogen succinate at 25°C and ionic strength I = 0.3 (KC1) was studied by pH-potentiometric titration. The stability constants of the complexes were determined.
Inverse Electron-Demand Diels-Alder Bioconjugation Reactions Using 7-Oxanorbornenes as Dienophiles
Agramunt, Jordi,Ginesi, Rebecca,Grandas, Anna,Pedroso, Enrique
, p. 6593 - 6604 (2020/07/14)
Oligonucleotides, peptides, and peptide nucleic acids incorporating 7-oxanorbornene as a dienophile were reacted with tetrazines linked to either a peptide, d-biotin, BODIPY, or N-acetyl-d-galactosamine. The inverse electron-demand Diels-Alder (IEDDA) cycloaddition, which was performed overnight at 37 °C, in all cases furnished the target conjugate in good yields. IEDDA reactions with 7-oxanorbornenes produce a lower number of stereoisomers than that of IEDDA cycloadditions with other dienophiles.
Cyclohexyl-Fused, Spirobiindane-Derived, Phosphine-Catalyzed Synthesis of Tricyclic ?3-Lactams and Kinetic Resolution of ?3-Substituted Allenoates
Wu, Mingyue,Han, Zhaobin,Li, Kaizhi,Wu, Ji'En,Ding, Kuiling,Lu, Yixin
supporting information, p. 16362 - 16373 (2019/10/16)
A C2-symmetric chiral phosphine catalyst, NUSIOC-Phos, which can be easily derived from cyclohexyl-fused spirobiindane, was introduced. A highly enantioselective domino process involving pyrrolidine-2,3-diones and γ-substituted allenoates catalyzed by NUSIOC-Phos has been disclosed. Diastereospecific tricyclic γ-lactams containing five contiguous stereogenic centers were obtained in high yields and with nearly perfect enantioselectivities. A kinetic resolution process of racemic γ-substituted allenoates was developed for the generation of optically enriched chiral allenoates.