318292-61-4 Usage
Uses
Ethyl 3-hydroxy-5-methoxy-1H-indole-2-carboxylate is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its presence of carboxylate, hydroxy, and methoxy functional groups allows for versatile chemical modifications, making it a valuable building block in the development of new drugs.
Used in Pharmaceutical Industry:
Ethyl 3-hydroxy-5-methoxy-1H-indole-2-carboxylate is used as a precursor in the synthesis of drugs with potential therapeutic applications. Its unique structure and functional groups enable the creation of molecules with specific biological activities, which can be further optimized for use in medicine.
Used in Research and Development:
Ethyl 3-hydroxy-5-methoxy-1H-indole-2-carboxylate is used as a research compound for studying the structure-activity relationships of indole-based molecules. This helps in understanding the molecular mechanisms underlying their biological activities and can guide the design of more effective therapeutic agents.
Used in Chemical Synthesis:
Ethyl 3-hydroxy-5-methoxy-1H-indole-2-carboxylate is used as a reagent in various chemical reactions, allowing for the formation of new compounds with different properties and applications. Its versatility in chemical transformations makes it a valuable tool in the synthesis of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 318292-61-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,8,2,9 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 318292-61:
(8*3)+(7*1)+(6*8)+(5*2)+(4*9)+(3*2)+(2*6)+(1*1)=144
144 % 10 = 4
So 318292-61-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H13NO4/c1-3-17-12(15)10-11(14)8-6-7(16-2)4-5-9(8)13-10/h4-6,13-14H,3H2,1-2H3
318292-61-4Relevant articles and documents
An efficient synthesis of LipidGreen and its derivatives via microwave assisted reaction and their live lipid imaging in zebrafish
Pagire, Haushabhau S.,Chun, Hang-Suk,Bae, Myung Ae,Ahn, Jin Hee
, p. 3039 - 3044 (2013/03/29)
We have developed an efficient synthesis of LipidGreen. The conversion is achieved by selective methylation with trimethylsilyldiazomethane, selective deprotection by BBr3 and an improved microwave-assisted C-allylation procedure. Using this ro
Synthesis of a new fluorescent small molecule probe and its use for in vivo lipid imaging
Lee, Jae Hong,So, Ju-Hoon,Jeon, Jong Hyun,Choi, Eun Bok,Lee, Yu-Ri,Chang, Young-Tae,Kim, Cheol-Hee,Bae, Myung Ae,Ahn, Jin Hee
, p. 7500 - 7502 (2011/08/07)
A new small molecule probe for in vivo lipid imaging, LipidGreen (compound 5), was developed. LipidGreen stained lipid droplets in 3T3L1 cell lines and fat deposits in zebrafish without apparent toxicity up to 100 μM. The utility of LipidGreen as a drug s
A concise synthesis of 3-hydroxyindole-2-carboxylates by a modified Baeyer-Villiger oxidation
Hickman,Sturino,Lachance
, p. 8217 - 8220 (2007/10/03)
Indole-2-carboxylates are converted in good yields to 3-hydroxyindole-2-carboxylates by use of a Vilsmeier-Haack/Baeyer-Villiger reaction sequence. A systematic examination of the various indole substituents revealed this route to be general in scope. (C) 2000 Published by Elsevier Science Ltd.
