32767-46-7Relevant articles and documents
Synthesis, characterization and in vitro antibacterial evaluation of 1-(7,7-dimethyl-2-morpholino-5,6,7,8-tetrahydroquinazolin-4-yl)piperidine-4-carboxamide derivatives
Selvakumar, Balaraman,Elango, Kuppanagounder P.
, p. 5535 - 5546 (2017)
A series of six novel 1-(7,7-dimethyl-2-morpholino-5,6,7,8-tetrahydroquinazolin-4-yl)piperidine-4-carboxamide derivatives has been synthesized and characterized using various spectral techniques (1H and 13C NMR, LCMS, IR). The antiba
Synthesis and antiviral study of 4-(7,7-dimethyl-4-(piperazin-1-yl)-5,6,7,8-tetrahydroquinazolin-2-yl) morpholine derivatives
Selvakumar, Balaraman,Gujjar, Naveen,Subbiah, Madhuri,Elango, Kuppanagounder P.
, p. 512 - 519 (2018)
Abstract: A series of 4-(7,7-dimethyl-4-(piperazin-1-yl)-5,6,7,8-tetrahydroquinazolin-2-yl)morpholine substituted sulfonamide and urea derivatives has been synthesized and characterized using spectral techniques. The antiviral activity of these compounds
Efficient synthesis of carbon-11 labelled acylsulfonamides using [11C]CO carbonylation chemistry
Van Der Wildt, Berend,Shen, Bin,Chin, Frederick T.
supporting information, p. 3124 - 3127 (2019/03/28)
Herein, a novel method for carbon-11 labeling of acyl sulfonamides by a one-step insertive [11C]CO carbonylative cross-coupling reaction between aryl halides and sulfonamides is presented. Various model compounds as well as drug molecules LY573636 (tasisulam) and ABT-199 were obtained in excellent yields. This method provides a valuable and widely applicable contribution to the continuously expanding radiochemical toolbox for PET research.
Sulfonamide derivative and application thereof in pharmacy
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Paragraph 0191; 0192; 0193, (2017/05/02)
The invention relates to a sulfonamide derivative and a pharmaceutical composition containing the same, and an application of the sulfonamide derivative and the pharmaceutical composition of the sulfonamide derivative in drug preparation, specifically the application in drug preparation of a BCL-2 family protein antagonist and the application in treatment of cancers.