33263-43-3 Usage
Description
4-Chloro-3-pyridinesulfonamide is an organic compound characterized by its off-white to light beige powder appearance. It is a building block used in the synthesis of various heterocyclic compounds, particularly those with potential pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
4-Chloro-3-pyridinesulfonamide is used as a reactant for the preparation of heterocyclic 4-substituted pyridine-3-sulfonamide derivatives. These derivatives serve as inhibitors of four isoforms of the zinc enzyme carbonic anhydrase, which are crucial in various physiological processes and can be targeted for the treatment of specific diseases.
Additionally, due to its chemical properties and reactivity, 4-Chloro-3-pyridinesulfonamide may also be utilized in other applications within the pharmaceutical industry, such as the development of new drugs or drug candidates targeting different enzymes or receptors.
Check Digit Verification of cas no
The CAS Registry Mumber 33263-43-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,2,6 and 3 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 33263-43:
(7*3)+(6*3)+(5*2)+(4*6)+(3*3)+(2*4)+(1*3)=93
93 % 10 = 3
So 33263-43-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H5ClN2O2S/c6-4-1-2-8-3-5(4)11(7,9)10/h1-3H,(H2,7,9,10)
33263-43-3Relevant articles and documents
PROCESS FOR THE PREPARATION OF HIGHLY PURE TORSEMIDE
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Page/Page column 31-32, (2010/02/07)
The present invention provides a novel process for the preparation of highly pure torsemide [1] by reacting of 4-m-tolylamino-3-pyridinesulfonamide [2] with phenyl isopropylcarbamate in the presence of lithium base (F I, II). The present invention also provides a novel intermediate - torsemide lithium, also in hydrate or solvate form - which is a stable, solid compound, and may be simply isolated from the reaction mixture to give after acidification practically pure torsemide [1] without further purification steps.
3-(Alkylamino)-4H-pyrido-1,2,4-thiadiazine 1,1-Dioxides as Powerful Inhibitors of Insulin Release from Rat Pancreatic B-Cells: A New Class of Potassium Channel Openers?
Pirotte, Bernard,Tullio, Pascal de,Lebrun, Philippe,Antoine, Marie-Helene,Fontaine, Jeanine,et al.
, p. 3211 - 3213 (2007/10/02)
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