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Usage

Uses

Used in Pharmaceutical Industry:
4-Amino-3-pyridinesulfonamide is used as a key intermediate in the synthesis of pharmaceuticals for its potential antineoplastic properties, making it a candidate for the development of treatments against cancer. Its structure allows for the creation of compounds that can target and inhibit the growth of tumor cells.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Amino-3-pyridinesulfonamide is utilized as a precursor in the production of antifungal agents, helping to protect crops from fungal infections and diseases, thereby ensuring higher crop yields and quality.
Used in the Synthesis of Novel Organic Compounds:
4-Amino-3-pyridinesulfonamide is employed as a building block in the synthesis of innovative organic compounds intended for medicinal purposes, broadening the scope of available treatments for various diseases and conditions.
Used in Treatment of Bacterial and Parasitic Infections:
Due to its antibacterial and antiparasitic properties, 4-Amino-3-pyridinesulfonamide has potential applications in the development of treatments for bacterial and parasitic infections, offering new therapeutic options for combating resistant strains and diseases.
It is crucial to handle 4-Amino-3-pyridinesulfonamide with care, given its potential hazards and the risks it may pose to human health and the environment. Proper safety measures and disposal methods should be strictly adhered to during its use in research, development, and manufacturing processes.

InChI:InChI=1/C5H7N3O2S/c6-4-1-5(3-8-2-4)11(7,9)10/h1-3H,6H2,(H2,7,9,10)

Upstream product

• 1071522-69-4 4-azidopyridine-3-sulfonic acid amide 
• 504-24-5 4-aminopyridine 
• 29452-57-1 4-amino-pyridine-3-sulfonic acid 
• 33263-43-3 4-chloropyridine-3-sulphonamide 
• 33263-44-4 4-chloro-pyridine-3-sulfonyl chloride 
• 51498-37-4 4-hydroxypyridine-3-sulfonic acid 

Downstream Products

• 163136-63-8 3-METHYL-2,3-DIHYDRO-4H-PYRIDO[4,3-e] [1,2,4]THIADIAZINE 1,1-DIOXIDE 
• 72811-73-5 3-sulfonamido-4-(3'-methylphenyl) aminopyridine 
• 1071519-46-4 (1R,2S,7R,8S)-5-(1,1-dioxo-1,4-dihydro-1λ6-pyrido[4,3-e][1,2,4]thiadiazin-3-yl)-3-(4-fluorobenzyl)-6-hydroxy-3-azatricyclo[6.2.1.02,7]undec-5-en-4-one 
• 204499-39-8 4-Bromo-N-(1,1-dioxo-1,4-dihydro-1λ⁶-pyrido[4,3-e][1,2,4]thiadiazin-3-ylmethyl)-benzamide 
• 216508-30-4 4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1,7-trioxide 

Relevant academic research and scientific papers

5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS

The invention is directed to 5,6-dihydro-lH-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.

Synthesis of pyrido-1,2,4-thiadiazines related to antihypertensive 1,2,4-benzothiadiazine-1,1-dioxides

Oxidation of 3-phenyl-2H-pyrido[2,3-e]-1,2,4-thiadiazine with sodium hypochlorite and, separately, m-chloroperoxybenzoic acid afforded a 1,1- dioxide and a 5-oxide derivative, respectively. Further examples of such 1,1- dioxide derivatives were synthesised by treating 2-amino-5-methylpyridine with orthoesters and these were subsequently oxidised to novel 1,1,5- trioxides. A short route has been developed for the synthesis of 4- aminopyridine-3-sulfonamide which was used for the preparation of 4H- pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides; oxidation of the parent member of the series gave a 1,1,7-trioxide derivative. 3-Aminopyridine-4-sulfonamide has been prepared, and then condensed with triethyl orthoformate to afford 4H-pyrido[3,4-e]-1,2,4-thiadiazine 1,1-dioxide.

Studies on Anticoccidial Agents. 13. Synthesis and Anticoccidial Activity of Nitropyridine-2- and -3-sulfonamides and Derivatives

Eight nitropyridinesulfonamides andd pyridinesulfonamide N-oxides as their bioisosteres were prepared and evaluated for anticoccidial activity.Of these compounds, 2-, 4- and 5-nitropyridine-3-sulfonamides and pyridine-2- and -3-sulfonamide N-oxides were found to be active against Eimeria tenella.Thus, the relative positions, ortho or meta, of the substituents in nitropyridine-3-sulfonamides and pyridinesulfonamide N-oxides are important for anticoccidial activity.N-Substituted analogues of 5-nitropyridine-3-sulfonamide were also prepared and optimal anticoccidial activity was attained with the sulfonamide and its lower N-alkyl derivatives.The mode of action of 5-nitropyridine-3-sulfonamide was examined and found to be active in the sporozoite and the first schizogony stages.