356783-27-2 Usage
Uses
Methyl 6-fluoro-3-hydroxypyrazine-2-carboxylate is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever.
Check Digit Verification of cas no
The CAS Registry Mumber 356783-27-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,6,7,8 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 356783-27:
(8*3)+(7*5)+(6*6)+(5*7)+(4*8)+(3*3)+(2*2)+(1*7)=182
182 % 10 = 2
So 356783-27-2 is a valid CAS Registry Number.
356783-27-2Relevant articles and documents
Novel pyrazine derivatives or salts thereof, pharmaceutical composition containing the same, and production intermediates thereof
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, (2008/06/13)
Pyrazine derivatives represented by general formula [1]: 1wherein the variables are as defined in the specification, or salts thereof have an excellent antiviral activity and are useful as a therapeutic agent for treating viral infections. Further, fluoropyrazine-carboxamide derivatives represented by general formula [2]: 2wherein the variables are as defined in the specification, or salts thereof are useful as an intermediate for production of the compounds of general formula [1], and as an intermediate for production of the fluoropyrazine-carboxamide derivatives of which one typical example is 6-fluoro-3-hyroxy-2-pyrazine-carboxamide having an antiviral activity.