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1,3-dihydroxyacetone oxime is a colorless solid chemical compound with a distinct odor, known for its solubility in water. It is commonly recognized as an industrial chelating agent and plays a significant role in the production of pharmaceuticals. Additionally, it is utilized in the synthesis of organic compounds, particularly in the formation of nitrogen-containing heterocyclic compounds. Classified as a skin sensitizer, it has the potential to cause irritation to the eyes and respiratory system.

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  • 37110-18-2 Structure
  • Basic information

    1. Product Name: 1,3-DIHYDROXYACETONE OXIME
    2. Synonyms: 1,3-DIHYDROXYACETONE OXIME;Dihydroxyacetoneoxime;1,3-DIHYDROXYACETONE OXIME 98+%
    3. CAS NO:37110-18-2
    4. Molecular Formula: C3H7NO3
    5. Molecular Weight: 105.09
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 37110-18-2.mol
  • Chemical Properties

    1. Melting Point: 84 °C
    2. Boiling Point: 350.2±27.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.36±0.1 g/cm3(Predicted)
    6. Refractive Index: 1.483
    7. Storage Temp.: Refrigerator
    8. Solubility: N/A
    9. PKA: 11.43±0.10(Predicted)
    10. Water Solubility: almost transparency
    11. CAS DataBase Reference: 1,3-DIHYDROXYACETONE OXIME(CAS DataBase Reference)
    12. NIST Chemistry Reference: 1,3-DIHYDROXYACETONE OXIME(37110-18-2)
    13. EPA Substance Registry System: 1,3-DIHYDROXYACETONE OXIME(37110-18-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 37110-18-2(Hazardous Substances Data)

37110-18-2 Usage

Uses

Used in Industrial Applications:
1,3-dihydroxyacetone oxime is used as a chelating agent in various industrial processes for its ability to bind with metal ions, which helps in preventing unwanted chemical reactions and improving the efficiency of certain processes.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1,3-dihydroxyacetone oxime is used as a key intermediate in the synthesis of various drugs, contributing to the development of new medicinal compounds.
Used in Organic Synthesis:
1,3-dihydroxyacetone oxime is utilized as a reagent in the synthesis of organic compounds, especially in the formation of nitrogen-containing heterocyclic compounds, which are important in various chemical and pharmaceutical applications.
Used in Cosmetics as a Tanning Agent:
In the cosmetics industry, 1,3-dihydroxyacetone oxime is used as a tanning agent. It reacts with amino acids in the skin to produce a temporary bronze color, providing a safe and effective alternative to sun exposure for achieving a tanned appearance.

Check Digit Verification of cas no

The CAS Registry Mumber 37110-18-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,1,1 and 0 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 37110-18:
(7*3)+(6*7)+(5*1)+(4*1)+(3*0)+(2*1)+(1*8)=82
82 % 10 = 2
So 37110-18-2 is a valid CAS Registry Number.
InChI:InChI=1/C3H7NO3/c5-1-3(2-6)4-7/h5-7H,1-2H2

37110-18-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-hydroxyiminopropane-1,3-diol

1.2 Other means of identification

Product number -
Other names D2412

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:37110-18-2 SDS

37110-18-2Upstream product

37110-18-2Relevant articles and documents

Kinetics and Mechanism of the Alkaline Release of Phenyl(mercapto)tetrazoles from α-Oximes

Boggs, Roger A.,Hasan, Fariza B.,Mahoney, J. Barry,Mehta, Avi C.,Palumbo, Catherine M. K.,et al.

, p. 1271 - 1277 (2007/10/02)

Compounds such as α-phenyl(mercapto)tetrazole (PMT) oxime (9) undergo rapid elimination of the PMT anion in base via a nitrosoene intermediate.Solution kinetics and HPLC analysis of reaction products are consistent with the mechanism shown in Scheme 2.For open chain oximes such as 4, substitution α to the oxime increases the rate of release of PMT and is attributed to the relief of strain when a crowded reactant is converted to a less-crowded product.For cyclic oximes, the six-membered ring compounds are more reactive than the corresponding five-membered compounds.A linear isokinetic relationship between the entropy and enthalpy of activation was found with β = 346 +/- 51 K.Entropies of activation were found to range from -7 to +24 c.u. (1 c.u. = 4.184 J mol-1 K-1) and support the proposed mechanism.

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