37945-37-2 Usage
Description
ETHYL 3-METHYL-4,5,6,7-TETRAHYDRO-1H-INDOLE-2-CARBOXYLATE is a chemical compound characterized by the molecular formula C15H19NO2. It is an ester derivative of indole carboxylic acid, known for its potential pharmacological properties and applications in the synthesis of various drugs within the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
ETHYL 3-METHYL-4,5,6,7-TETRAHYDRO-1H-INDOLE-2-CARBOXYLATE is used as a key intermediate in the synthesis of drugs for the treatment of certain medical conditions. Its unique chemical structure and properties make it a valuable component in the development of novel therapeutic agents.
In the synthesis of various drugs, ETHYL 3-METHYL-4,5,6,7-TETRAHYDRO-1H-INDOLE-2-CARBOXYLATE serves as a building block, contributing to the formation of the desired active pharmaceutical ingredients. Its presence in these compounds can enhance their efficacy, selectivity, and pharmacokinetic properties, ultimately leading to improved treatment outcomes for patients.
It is crucial to handle ETHYL 3-METHYL-4,5,6,7-TETRAHYDRO-1H-INDOLE-2-CARBOXYLATE with care and adhere to proper safety protocols when working with it in laboratory settings. This ensures the safety of researchers and the integrity of the experiments conducted using this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 37945-37-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,9,4 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 37945-37:
(7*3)+(6*7)+(5*9)+(4*4)+(3*5)+(2*3)+(1*7)=152
152 % 10 = 2
So 37945-37-2 is a valid CAS Registry Number.
37945-37-2Relevant articles and documents
Porphyrins with Exocyclic Rings. 1. Chemistry of 4,5,6,7-Tetrahydro-1H-indoles: Synthesis of Acetoxy Derivatives, Dihydroindoles, and Novel Porphyrins with Four Exocyclic Rings
Lash, Timothy D.,Bladel, Karla A.,Shiner, Craig M.,Zajeski, Donna L.,Balasubramaniam, Rajiv P.
, p. 4809 - 4820 (2007/10/02)
A variety of 4,5,6,7-tetrahydro-1H-indoles (THI's) and 4-oxo-4,5,6,7-tetrahydro-1-indoles (4-oxoTHI's) have been synthesized from cyclohexanone and 1,3-cyclohexanedione, respectively.The THI's reacted regioselectively with lead tetraacetate in acetic acid
Regioselectivity of Pyrrole Synthesis fromm Diethyl Aminomalonate and 1,3-Diketones: Further Observations
Paine, John B.,Brough, Jonathan R.,Buller, Kathy K.,Erikson, Erika E.
, p. 3986 - 3993 (2007/10/02)
1,3-Diketones 1 react with diethyl aminomalonate (2) in boiling acetic acid to afford ethyl 2-pyrrolecarboxylates 6.Considerable regioselectivity was noted for the following classes of diketone: 2-acylcyclohexanones 10a,b , 2-acylcyclopentanones 10c,d pyrroles 13a,b>, 1-phenyl-2-alkyl-1,3-alkanediones 17a-d , 3-phenyl-2,4-hexanedione (21a) , 1-phenyl-3-alkyl-2,4-alkanediones 24a,b , and 2,2-dimethyl-3,5-alkanediones 29a,b .The yields varied with the structural class, decreasing with increased steric hindrance.The product structure correlated with the structure of the enolized diketones in the case of the 2-acylcycloalkanones studied.