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6-nitro-9-methyl-2,3,4,9-tetrahydro-1H-carbazole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 39581-69-6 Structure
  • Basic information

    1. Product Name: 6-nitro-9-methyl-2,3,4,9-tetrahydro-1H-carbazole
    2. Synonyms: 6-nitro-9-methyl-2,3,4,9-tetrahydro-1H-carbazole
    3. CAS NO:39581-69-6
    4. Molecular Formula: C13H14N2O2
    5. Molecular Weight: 230.26246
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 39581-69-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 6-nitro-9-methyl-2,3,4,9-tetrahydro-1H-carbazole(CAS DataBase Reference)
    10. NIST Chemistry Reference: 6-nitro-9-methyl-2,3,4,9-tetrahydro-1H-carbazole(39581-69-6)
    11. EPA Substance Registry System: 6-nitro-9-methyl-2,3,4,9-tetrahydro-1H-carbazole(39581-69-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 39581-69-6(Hazardous Substances Data)

39581-69-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 39581-69-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,5,8 and 1 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 39581-69:
(7*3)+(6*9)+(5*5)+(4*8)+(3*1)+(2*6)+(1*9)=156
156 % 10 = 6
So 39581-69-6 is a valid CAS Registry Number.

39581-69-6Relevant articles and documents

Synthesis and evaluation of 2,3,4,9-tetrahydro-1H-carbazole derivatives as selective acetylcholinesterase inhibitors: Potential anti-Alzheimer's agents

Kukreja, Hitesh,Chugh, Rajan,Singh, Jatinder,Shah, Ramanpreet,Singh, Dhandeep,Singh, Nirmal,Chopra, Dimple Sethi,Singh, Mandeep

, p. 152 - 160 (2021/09/28)

Alzheimer's disease is an irreversible, progressive brain disorder that slowly destroys memory and cognition skills. Dysfunction of acetylcholine containing neurons in the brain contributes substantially to the cognitive decline observed in Alzheimer's disease. Hence, our focus is to synthesize cholinesterase inhibitors. A series (22 compounds) of 6- and 9-substituted derivatives of 2,3,4,9-tetrahydro-1H-carbazole have been prepared and in vitro evaluated for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibition by Ellman's method. By comparing selectivity with standard drug donepezil, amino derivative 3, methylamino derivative 4 and butyl nitro derivative 17 have been found to be selective AChE inhibitors. Borsche-Drechsel cyclization reaction has been carried out to synthesize 2,3,4,9-tetrahydrocarbazole ring followed by nitration, reduction and derivative synthesis.

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