40493-34-3

Basic information

• Product Name: 1-(benzo[d][1,3]dioxol-5-yl)-2-chloroethan-1-ol
• CAS NO: 40493-34-3
• Molecular Weight: 200.622
• Mol File: 40493-34-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(benzo[d][1,3]dioxol-5-yl)-2-chloroethan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(benzo[d][1,3]dioxol-5-yl)-2-chloroethan-1-ol(40493-34-3)
• EPA Substance Registry System: 1-(benzo[d][1,3]dioxol-5-yl)-2-chloroethan-1-ol(40493-34-3)

Safety Data

• Hazardous Substances Data: 40493-34-3(Hazardous Substances Data)

Upstream product

• 120-57-0 piperonal 
• 75-09-2 dichloromethane 
• 7315-32-4 5-vinyl-1,3-benzodioxole 
• 6329-73-3 1-benzo[1,3]dioxol-5-yl-ethanol 

Downstream Products

• 5530-29-0 2-chloro-1-(3,4-dihydroxy-phenyl)-ethanol 

Relevant articles and documents

A new entry of highly selective and nucleophilic BrH2C-and CLH2c-titanium complexes for carbonyl coupling

The direct coupling of various aldehydes and ketones with CH2Br2 or CH2Cl2 promoted by TiCl4-Mg bimetallic complex provides an extremely simple, practical, and efficient approach for the construction of bromomethyl or chloromethyl carbinols. The high chemoselectivity of this chemistry is illus-trated by the TiCl4-Mg-promoted selective coupling of CH2Br2 or CH2Cl2 with an aldehyde in the presence of ketone and selective transfer of CH2Br or CH2Cl to saturated carbonyl moiety. This protocol is also suitable for sterically hindered and enoliza-ble carbonyl compounds.