4156-59-6 Usage
General Description
3,4,5-Trimethoxybenzo-amidite hydrochloride is a chemical compound used in the synthesis of organic molecules. It is commonly employed as a reagent in the production of peptides and oligonucleotides. 3,4,5-TRIMETHOXYBENZO-AMIDITE HYDROCLORIDE consists of a benzene ring with three methoxy groups and an amide functional group attached to it. The hydrochloride salt form of this compound enhances its solubility and stability, making it easier to handle and store. 3,4,5-Trimethoxybenzo-amidite hydrochloride is an important building block in organic chemistry and is widely utilized in the pharmaceutical and biotechnology industries for the production of various drugs and biologically active compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 4156-59-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,5 and 6 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4156-59:
(6*4)+(5*1)+(4*5)+(3*6)+(2*5)+(1*9)=86
86 % 10 = 6
So 4156-59-6 is a valid CAS Registry Number.
4156-59-6Relevant articles and documents
Facile synthesis of 3,5-diaryl-1,2,4-triazoles via copper-catalyzed domino nucleophilic substitution/oxidative cyclization using amidines or imidates as substrates
Sudheendran, Kavitha,Schmidt, Dietmar,Frey, Wolfgang,Conrad, Jürgen,Beifuss, Uwe
, p. 1635 - 1645 (2014/02/14)
Two methods for the synthesis of 3,5-diaryl-1,2,4-triazoles, both domino reactions, are reported. The first procedure, the Cu(OTf)2-catalyzed reaction between two amidines using NaHCO3 as a base, 1,10-phenanthroline as an additive and K3[Fe(CN)6]/ atmospheric oxygen as the oxidant, delivers 3,5-diaryl-1,2,4-triazoles with yields up to 68%. The second procedure for the synthesis of 3,5-diaryl-1,2,4- triazoles with yields up to 64% rests on the Cu(OTf)2-catalyzed reaction between two imidates and ammonium carbonate. This method features the formation of three bonds in a single synthetic step.