42031-02-7Relevant articles and documents
Ultrasound-assisted synthesis of 2,5-dimethyl-N-substituted pyrroles catalyzed by uranyl nitrate hexahydrate
Satyanarayana,Sivakumar
scheme or table, p. 917 - 922 (2012/03/08)
An efficient synthesis of different novel 2,5-dimethyl-N-substituted pyrrole derivatives by the Paal-Knorr condensation has been accomplished using uranyl nitrate hexahydrate as catalyst under soft conditions and ultrasonic irradiation. The synthesized compounds were confirmed through spectral characterization using IR, 1H NMR, 13C NMR and mass spectra.
Dihydroxy aromatic compounds and methods for preparation
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Page/Page column 16-17, (2010/11/25)
A dihydroxy aromatic compound having a Formula (I), wherein R1 is a C6–C60 aromatic divalent functionality, R2 at each occurrence, can be the same or different and is independently at each occurrence selected from the group consisting of a cyano functionality, a nitro functionality, a halogen, an aliphatic functionality having 1 to 10 carbons, a cycloaliphatic functionality having 3 to 10 carbons and an aromatic functionality having 6 to 10 carbons, and “n” is an integer having a value of 0 to 4.
Tryptase inhibitors
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, (2008/06/13)
The invention relates to novel inhibitors of human tryptase which are used in the pharmaceutical industry for the production of medicaments.
Molecular recognition of β-ribofuranosides by synthetic polypyridine-macrocyclic receptors
Inouye, Masahiko,Miyake, Toshiyuki,Furusyo, Masaru,Nakazumi, Hiroyuki
, p. 12416 - 12425 (2007/10/03)
Artificial ribofuranoside receptors were designed and synthesized. The design of the polypyridine-macrocyclic receptors was based on the multipoint hydrogen bond complementarity between the receptors and methyl β-D-ribofuranoside. The binding affinity of the receptors for the ribofuranoside in CDCl3 was very high (up to K(a) = 5.2 x 103 M-1), so that even native ribose was extracted by them into such nonpolar solvents. Selective extraction of ribose by the receptors was observed: the extractabilities, or affinities to the receptors of various pentoses and hexoses decreased in the following order: ribose > deoxyribose ? lyxose ? xylose > fructose > arabinose > glucose ? mannose ? galactose. The selectivity is governed by the OH direction and the whole size of the sugars as well as their shapes. Furthermore, fluorescence emission of the receptors was largely enhanced in the presence of methyl β-D-ribofuranoside or ribose, and the degree for the fluorescence enhancement by the addition of various sugars was almost compatible with that of the extractabilities. The polypyridine-macrocycles represent rationally designed multifunctional artificial receptors for ribofuranosides.