42413-70-7

Basic information

• Product Name: 3,6-Pyridazinedione
• Synonyms: 3,6-Pyridazinedione
• CAS NO: 42413-70-7
• Molecular Formula: C₄H₂N₂O₂
• Molecular Weight: 110.07088
• Mol File: 42413-70-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3,6-Pyridazinedione(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-Pyridazinedione(42413-70-7)
• EPA Substance Registry System: 3,6-Pyridazinedione(42413-70-7)

Safety Data

• Hazardous Substances Data: 42413-70-7(Hazardous Substances Data)

Upstream product

• 123-33-1 Maleic hydrazide 
• 123-33-1 3,6-dihydroxypyridazine 
• 141-30-0 3,6-dichlorpyridazine 
• 28330-26-9 1,2-dihydropyridazine-3,6-dione, sodium salt 

Downstream Products

• 141-30-0 3,6-dichlorpyridazine 
• 135800-28-1 trans-3-benzyl-3,4-dihydro-4-<(1,6-dihydro-6-oxo-3-pyridazinyl)oxy>-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-carbonitrile 
• 124926-11-0 1-(2-oxo-4,6,6-trimethyl-3-cyclohexenyl)-3-hydroxypyridazin-6-one 

Relevant articles and documents

Creation and manipulation of common functional groups en route to a skeletally diverse chemical library

We have developed an efficient strategy to a skeletally diverse chemical library, which entailed a sequence of enyne cycloisomerization, [4 + 2] cycloaddition, alkene dihydroxylation, and diol carbamylation. Using this approach, only 16 readily available building blocks were needed to produce a representative 191-member library, which displayed broad distribution of molecular shapes and excellent physicochemical properties. This library further enabled identification of a small molecule, which effectively suppressed glycolytic production of ATP and lactate in CHO-K1 cell line, representing a potential lead for the development of a new class of glycolytic inhibitors.

Regioselective aluminium chloride induced heteroarylation of pyrrolo[1,2-b]pyridazines: Its scope and application

We describe a detailed study on the novel synthesis of 6,7-disubstituted pyrrolo[1,2-b]pyridazines through AlCl3 induced C-C bond formation reactions. A wide variety of 6-aryl substituted azolopyridazines was reacted with 3,6-dichloropyridazine to give 7-pyridazinyl substituted pyrrolopyridazines regioselectively in good to excellent yield. The mechanism and regiochemistry of the reaction along with applications of the methodology are discussed.