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141-30-0 Usage


3,6-Dichloropyridazine is an off-white to brownish crystalline powder that serves as a crucial intermediate in synthetic chemistry, particularly in the development of active pharmaceutical ingredients.


Used in Pharmaceutical Industry:
3,6-Dichloropyridazine is used as a synthetic intermediate for the creation of various active pharmaceutical ingredients. Its chemical properties make it a valuable compound in the development of new drugs and therapies.
Used in Chemical Synthesis:
3,6-Dichloropyridazine is utilized in the preparation of alfa-(halohetaroyl)-2-azahetarylacetonitriles, which are important compounds in the field of chemical synthesis. This application highlights its versatility and importance in the synthesis of complex molecules for various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 141-30-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 1 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 141-30:
30 % 10 = 0
So 141-30-0 is a valid CAS Registry Number.

141-30-0 Well-known Company Product Price

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  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (A14795)  3,6-Dichloropyridazine, 98%   

  • 141-30-0

  • 25g

  • 275.0CNY

  • Detail
  • Alfa Aesar

  • (A14795)  3,6-Dichloropyridazine, 98%   

  • 141-30-0

  • 100g

  • 662.0CNY

  • Detail
  • Alfa Aesar

  • (A14795)  3,6-Dichloropyridazine, 98%   

  • 141-30-0

  • 500g

  • 3000.0CNY

  • Detail
  • Aldrich

  • (D73200)  3,6-Dichloropyridazine  97%

  • 141-30-0

  • D73200-25G

  • 415.35CNY

  • Detail
  • Aldrich

  • (D73200)  3,6-Dichloropyridazine  97%

  • 141-30-0

  • D73200-100G

  • 986.31CNY

  • Detail
  • Aldrich

  • (D73200)  3,6-Dichloropyridazine  97%

  • 141-30-0

  • D73200-500G

  • 4,079.79CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017


1.1 GHS Product identifier

Product name 3,6-Dichloropyridazine

1.2 Other means of identification

Product number -
Other names 3,6-Dichloro-1,2-diazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:141-30-0 SDS

141-30-0Relevant articles and documents

Intermolecular contacts in the crystal structures of specifically varied halogen and protonic group substituted azines

Hübscher, J?rg,Seichter, Wilhelm,Weber, Edwin

, p. 3026 - 3036 (2017)

A series of azines featuring differently halogen and protic group substituted pyridine, pyrimidine and pyridazine compounds have been synthesized and studied in terms of their crystal structures in order to develop a better understanding of the links between structural conditions and molecular packing behavior. Complemented by the structure results of related compounds known from the literature, intermolecular contact relationships connected to the present substance types were found, having potential use in future crystal engineering of similar compounds. This primarily involves the formation of N?I contacts aside from specific halogen?halogen and hydrogen bond type interactions.

Polymorph-specific chlorination of maleic-hydrazide

Katrusiak, Andrzej,Katrusiak, Anna

, p. 203 - 210 (2003)

The reaction of chlorination of maleic-hydrazide (1) with POC13 is specific to the substrate polymorph. Chlorination of either the triclinic polymorph of maleic-hydrazide (1), denoted MH1, or the monoclinic polymorph MH2 leads to a single product of 3,6-dichloropyridazine (2), while chlorination of the monoclinic polymorph MH3 under the same conditions results in two products: 3,6-dichloropyridazine (2) and 6-chloro-3-pyridazinone (3). The structural differences between polymorphs and their topochemical chlorination in phosphorus oxychloride are discussed. The crystal structure of 6-chloro-3-pyridazinone (3) monohydrate, determined in this study by X-ray diffraction, is built of ribbons of hydrogen-bonded 3 and water molecules. It has been established that the chlorination of ground crystals of polymorph MH3 yields exclusively the dichloropyridazine, which suggests that the crystal habit of MH3, the size of crystallites and the lower solubility of MH3 than MH1 and MH2 are the main reasons for the different course of the reaction.

Pyridazine N-Oxides as Photoactivatable Surrogates for Reactive Oxygen Species

Basistyi, Vitalii S.,Frederich, James H.

supporting information, p. 1907 - 1912 (2022/03/27)

A method for the photoinduced evolution of atomic oxygen from pyridazine N-oxides was developed. This underexplored oxygen allotrope mediates arene C-H oxidation within complex, polyfunctional molecules. A water-soluble pyridazine N-oxide was also developed and shown to promote photoinduced DNA cleavage in aqueous solution. Taken together, these studies highlight the utility of pyridazine N-oxides as photoactivatable O(3P) precursors for applications in organic synthesis and chemical biology.

Preparation method of 3, 6-dichloropyridazine


Paragraph 0034-0039, (2021/04/14)

The invention belongs to the technical field of medicines, and particularly relates to a preparation method of 3, 6-dichloropyridazine. The preparation method comprises the following steps: carrying out chlorination reaction on 3, 6-dihydroxypyridazine and N-chlorosuccinimide to generate 3, 6-dichloropyridazine; the chlorination reaction route is as follows: the method solves the technical problems of large environmental pollution, high process risk and high cost due to the adoption of the traditional chlorinating agent in the existing 3, 6-dichloropyridazine preparation method.

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